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Y0000079

Articaine hydrochloride

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

4-Methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylic acid methyl ester hydrochloride, Carticaine chlorhydrate, Carticaine hydrochloride

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About This Item

Formule empirique (notation de Hill):
C13H20N2O3S · HCl
Numéro CAS:
23964-57-0
Poids moléculaire :
320.84
Numéro MDL:
MFCD00190157
Code UNSPSC :
41116107
ID de substance PubChem :
329830834
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

articaine

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

CC1=CSC(C(OC)=O)=C1NC(C(C)NCCC)=O.Cl

InChI

1S/C13H20N2O3S.ClH/c1-5-6-14-9(3)12(16)15-10-8(2)7-19-11(10)13(17)18-4;/h7,9,14H,5-6H2,1-4H3,(H,15,16);1H

Clé InChI

GDWDBGSWGNEMGJ-UHFFFAOYSA-N

Informations sur le gène

human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

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Catégories apparentées

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Articaine hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Actions biochimiques/physiologiques

Articaine is an amide local anesthetic widely used in dentistry. Articaine acts by inhibition of nerve impulse conduction by blockade of sodium channels.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Y0000081

Articaine impurity E, European Pharmacopoeia (EP) Reference Standard

1042918

Articaine hydrochloride, United States Pharmacopeia (USP) Reference Standard

1042907

Articaine, United States Pharmacopeia (USP) Reference Standard

1042929

Articaine Related Compound A, United States Pharmacopeia (USP) Reference Standard

1042930

Articaine Related Compound B, United States Pharmacopeia (USP) Reference Standard

1042962

Articaine Related Compound E, United States Pharmacopeia (USP) Reference Standard

PHR1882

Articaine, Pharmaceutical Secondary Standard; Certified Reference Material

07356

4-Methyl-N-propyl-3-[[(2RS)-2-(propylamino)propanoyl]amino]thiophene-2-carboxamide hydrochloride, reference material

07380

1-Methylethyl 4-methyl-3-[[(2RS)-2-(propylamino)-propanoyl]amino]thiophene-2-carboxylate hydrochloride, reference material

CRM69760

Methyl 3-[[(2RS)-2-bromopropanoyl]amino]-4-methylthiophene-2-carboxylate, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

CRM72531

Methyl 3-[[(2RS)-2-(ethylamino)propanoyl]amino]-4-methylthiophene-2- carboxylate hydrochloride, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H315,H319,H335

Classification des risques

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Khalid E El-Kholey
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 71(10), 1658-1658 (2013-09-18)
Profound anesthesia for mandibular molars by buccal infiltration has been tried in recent years, with promising results. This prospective, randomized, single-blinded, crossover study investigated the clinical anesthetic efficacy obtained with 1:100,000 epinephrine plus 4% articaine (A100) 1.8 versus 3.6 mL
Lei Dou et al.
Quintessence international (Berlin, Germany : 1985), 44(5), 457-464 (2013-03-13)
The aim of this systematic review is to investigate the effect of an additional lingual infiltration on the pulpal anesthesia of mandibular teeth. Prospective clinical trials were searched from Medline, EMBASE, Cochrane Library, Pubmed, SCI, and the China National Knowledge
J G Förster et al.
Acta anaesthesiologica Scandinavica, 57(7), 911-919 (2013-03-26)
Articaine and chloroprocaine have recently gained interest as short-acting spinal anaesthetics. Based on previous work comparing articaine 60 mg with chloroprocaine 40 mg, we hypothesised that articaine 40 mg and chloroprocaine 40 mg would produce similar spinal anaesthesa regarding block onset, maximal spread, and
Denis Medvedev et al.
Oral health and dental management, 11(3), 95-99 (2012-09-15)
This pilot prospective, randomised, crossover study of positive aspiration frequency in intra-ligamental anaesthesia (ILA) was conducted with the following aims: (1) to determine the frequency of positive aspiration of blood after the administration of ILA at lower first molars, and
Hengameh Ashraf et al.
Journal of endodontics, 39(1), 6-10 (2012-12-12)
Profound pulpal anesthesia in posterior mandibular teeth with irreversible pulpitis usually requires administering an inferior alveolar nerve block (IANB) plus other supplemental injections. The purpose of this prospective, randomized, double-blind study was to compare the anesthetic success rate of buccal
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