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SMB01331

Sigma-Aldrich

Dopamine 4-sulfate

Synonyme(s) :

3-Hydroxytyramine-4-O-sulfate, Dopamine 4-O-sulfate, Dopamine sulfate

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About This Item

Formule empirique (notation de Hill):
C8H11NO5S
Numéro CAS:
Poids moléculaire :
233.24
Numéro MDL:
Code UNSPSC :
12352116
Nomenclature NACRES :
NA.77

Pureté

≥95% (HPLC)

Niveau de qualité

Forme

solid

Composition

[4-(2-Aminoethyl)-2-hydroxyphenyl]oxidanesulfonic acid

Concentration

≤100%

Couleur

white to beige

Pf

265—270.5 °C

Groupe fonctionnel

amine

Température de stockage

−20°C

InChI

1S/C8H11NO5S/c9-4-3-6-1-2-8(7(10)5-6)14-15(11,12)13/h1-2,5,10H,3-4,9H2,(H,11,12,13)

Clé InChI

DEKNNWJXAQTLFA-UHFFFAOYSA-N

Description générale

Dopamine 4-sulfate is a major circulating plasma metabolite and urinary metabolite of dopamine formed by cytosolic sulfotransferase 1A3 (SULT1A3) from both exogenous and endogenous dopamine. Dopamine 4-sulfate has been shown to bind to the GABA receptor, but not to D1 or D2 dopamine receptors. Dopamine 4-sulfate is 10 times more abundant than isomeric dopamine 3-sulfate and is considered a potential biomarker for banana and other fruits consumption.

Application

Metabolomics research

Autres remarques

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Pictogrammes

Exclamation mark

Mention d'avertissement

Warning

Mentions de danger

Classification des risques

Eye Irrit. 2 - Skin Irrit. 2

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Katriina Itäaho et al.
Biochemical pharmacology, 74(3), 504-510 (2007-06-06)
SULT1A3 is an enzyme that catalyzes the sulfonation of many endogenous and exogenous phenols and catechols. The most important endogenous substrate is dopamine (DA), which is often used as a probe substrate for SULT1A3. We developed a new method for
N Vázquez-Manjarrez et al.
Genes & nutrition, 15(1), 11-11 (2020-06-21)
Consumption of fruit and vegetable is a key component of a healthy and sustainable diet. However, their accurate dietary assessment remains a challenge. Due to errors in self-reporting methods, the available dietary information is usually biased. Biomarkers of intake constitute
Tina Suominen et al.
PloS one, 10(7), e0133904-e0133904 (2015-07-25)
Dopamine sulfate (DA-3- and DA-4-S) have been determined in the human brain, but it is unclear whether they are locally formed in the central nervous system (CNS), or transported into the CNS from peripheral sources. In the current study, permeation

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