M1511
Sodium 2-mercaptoethanesulfonate
analytical standard, ≥98.0% (titration)
Synonyme(s) :
2-Mercaptoethanesulfonic acid sodium salt, Coenzyme M sodium salt, HS-CoM Na, MESNA
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About This Item
Formule linéaire :
HSCH2CH2SO3Na
Numéro CAS:
Poids moléculaire :
164.18
Numéro Beilstein :
3657828
Numéro CE :
Numéro MDL:
Code UNSPSC :
41116107
ID de substance PubChem :
Nomenclature NACRES :
NA.24
Produits recommandés
Qualité
analytical standard
Niveau de qualité
Pureté
≥98.0% (titration)
Technique(s)
HPLC: suitable
gas chromatography (GC): suitable
Application(s)
clinical testing
Format
neat
Chaîne SMILES
[Na+].[O-]S(=O)(=O)CCS
InChI
1S/C2H6O3S2.Na/c3-7(4,5)2-1-6;/h6H,1-2H2,(H,3,4,5);/q;+1/p-1
Clé InChI
XOGTZOOQQBDUSI-UHFFFAOYSA-M
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Description générale
Sodium 2-mercaptoethanesulfonate is a thiol compound commonly used as an auxiliary drug, to reduce the side effects of anti-cancer drugs, such as oxazaphosphorine, cyclophosphamide, and ifosfamide. It acts by forming a non-toxic compound upon reacting with the toxic metabolites of the drugs like acrolein.
Application
The analytical standard can also be used as follows:
- Quantification of sodium 2-mercaptoethanesulfonate (MESNA) from human samples by micellar electrokinetic chromatography (MEKC) coupled with UV detection and in-capillary derivatization of MESNA
- Development of a fluorescence-enhanced histidine stabilized gold nanoclusters (His-Au NCs) based probe for the detection of sodium 2-mercaptoethanesulfonate in uromitexan samples
- High-performance liquid chromatography-tandem mass spectrometric based bioanalysis of sodium 2-mercaptoethanesulfonate in rat plasma samples
- To quantify sodium 2-mercaptoethanesulfonate in two of its pharmaceutical preparations (injections) by surface-enhanced Raman scattering (SERS) using gold colloid as a probe
Autres remarques
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Mention d'avertissement
Warning
Mentions de danger
Conseils de prudence
Classification des risques
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Organes cibles
Respiratory system
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 2
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Équipement de protection individuelle
dust mask type N95 (US), Eyeshields, Gloves
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