D0710000

Dexamethasone 21-acetate

European Pharmacopoeia (EP) Reference Standard

• Synonyme(s) : Dexamethasone 21-acetate, 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione-21-acetate, 9α-Fluoro-16α-methylprednisolone-21-acetate, Prednisolone F acetate
• Formule empirique (notation de Hill) : C₂₄H₃₁FO₆
• Numéro CAS: 1177-87-3
• Poids moléculaire : 434.50
• Beilstein: 2342608
• Numéro MDL: MFCD00027407
• Code UNSPSC : 41116107
• ID de substance PubChem : 329798629
• Nomenclature NACRES : NA.24

Propriétés

• Source biologique: synthetic
• Qualité: pharmaceutical primary standard
• Agence: EP
• Famille d'API: dexamethasone
• Conditionnement: pkg of 150 mg
• Fabricant/nom de marque: EDQM
• Conditions de stockage: protect from light
• Couleur: white
• Solubilité: water: <0.1 g/L
• Application(s): pharmaceutical (small molecule)
• Format: neat
• Conditions d'expédition: ambient
• Température de stockage: 2-8°C
• Chaîne SMILES: [H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@@H](C)[C@]4(O)C(=O)COC(C)=O
• InChI: 1S/C24H31FO6/c1-13-9-18-17-6-5-15-10-16(27)7-8-21(15,3)23(17,25)19(28)11-22(18,4)24(13,30)20(29)12-31-14(2)26/h7-8,10,13,17-19,28,30H,5-6,9,11-12H2,1-4H3/t13-,17+,18+,19+,21+,22+,23+,24+/m1/s1
• Clé InChI: AKUJBENLRBOFTD-RPRRAYFGSA-N
• Informations sur le gène: human ... NR3C1(2908)

Description

Description générale

Dexamethasone acetate (Decadron-LA) belongs to the class of long-acting glucocorticoids,[1] commonly used as a pharmaceutical ingredient in creams,[2] ointments,[3] microemulsions, lotions, aerosols, etc.[4]
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Dexamethasone acetate is used as an EP reference standard to quantify the analyte in pharmaceutical formulations using chromatography ttechniques.[5][2][3]

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Informations sur la sécurité

• Pictogrammes: GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H360FD
• Conseils de prudence: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Classification des risques: Repr. 1B
• Code de la classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 3