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MAB5456

Sigma-Aldrich

Anti-Gonadotropin-Releasing Hormone Antibody, NT, clone HU11B

ascites fluid, clone HU11B, Chemicon®

Synonyme(s) :

GnRH, Luteinizing Hormone-Releasing Hormone, LHRH

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

mouse

Forme d'anticorps

ascites fluid

Type de produit anticorps

primary antibodies

Clone

HU11B, monoclonal

Espèces réactives

hamster, shrimp, mouse, monkey, rat

Fabricant/nom de marque

Chemicon®

Technique(s)

immunohistochemistry: suitable (paraffin)

Isotype

IgG1

Numéro d'accès NCBI

Numéro d'accès UniProt

Conditions d'expédition

dry ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

mouse ... Gnrh1(14714)

Spécificité

Reacts with mammalian Gonadotropin-releasing hormone.

Immunogène

Epitope: N-terminus
Mouse GnRH (QHWSYGLRPG) conjugated to bovine thyroglobulin.

Application

Immunohistochemistry on 4% paraformaldehyde fixed tissue sections.

Immunocytochemistry

Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Hormones & Receptors
This Anti-Gonadotropin-Releasing Hormone Antibody, N-terminus, clone HU11B is validated for use in IH(P) for the detection of Gonadotropin-Releasing Hormone.

Forme physique

Ascites fluid. Liquid. Contains no preservative.

Stockage et stabilité

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Santiago E Charif et al.
Physiological reports, 5(19) (2017-10-19)
Females of the South American plains vizcacha, Lagostomus maximus, show peculiar reproductive features such as massive polyovulation up to 800 oocytes per estrous cycle and an ovulatory process around mid-gestation arising from the reactivation of the hypothalamic-hypophyseal-ovary (H.H.O.) axis. Estradiol
S E Rietema et al.
Reproduction, fertility, and development, 31(11), 1682-1691 (2019-09-13)
Rams respond to acute nutritional supplementation by increasing the frequency of gonadotrophin-releasing hormone (GnRH) pulses. Kisspeptin neurons may mediate the effect of environmental cues on GnRH secretion, so we tested whether the ram response to nutrition involves activation of kisspeptin
Aleisha M Moore et al.
Scientific reports, 8(1), 2242-2242 (2018-02-06)
Kisspeptin/Neurokinin B/Dynorphin (KNDy) neurons of the arcuate nucleus (ARC) play a key role in the regulation of fertility. The ability to detect features of KNDy neurons that are essential for fertility may require three-dimensional (3D) imaging of the complete population.
Diana E Peragine et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(5), 1207-1212 (2017-01-18)
Neuroendocrine mechanisms underlying social inhibition of puberty are not well understood. Here, we use a model exhibiting the most profound case of pubertal suppression among mammals to explore a role for RFamide-related peptide-3 [RFRP-3; mammalian ortholog to gonadotropin-inhibitory hormone (GnIH)]
Yang Li et al.
PloS one, 17(6), e0259609-e0259609 (2022-06-16)
Polycystic ovary syndrome often starts in puberty, and its pathogenesis is not clear. This study aimed to explore the pathogenesis of pubertal polycystic ovary syndrome (PCOS) and assess the therapeutic effect of electroacupuncture on pubertal PCOS. Dihydrotestosterone (DHT) was used

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