8.52220

Fmoc-Asp-OBzl

Novabiochem^®

• Synonyme(s) : Fmoc-Asp-OBzl, N-α-Fmoc-L-aspartic acid α-benzyl ester
• Formule empirique (notation de Hill): C₂₆H₂₃NO₆
• Numéro CAS: 86060-83-5
• Poids moléculaire : 445.46
• Code UNSPSC : 12352209
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 200
• Gamme de produits: Novabiochem^®
• Pureté: ≥90.0% (acidimetric); ≥98% (TLC); ≥98.0% (HPLC)
• Forme: powder
• Capacité de réaction: reaction type: Fmoc solid-phase peptide synthesis
• Fabricant/nom de marque: Novabiochem^®
• Application(s): peptide synthesis
• Groupe fonctionnel: carboxylic acid
• Température de stockage: 2-30°C
• InChI: 1S/C26H23NO6/c28-24(29)14-23(25(30)32-15-17-8-2-1-3-9-17)27-26(31)33-16-22-20-12-6-4-10-18(20)19-11-5-7-13-21(19)22/h1-13,22-23H,14-16H2,(H,27,31)(H,28,29)/t23-/m0/s1
• Clé InChI: CBZSVHFNEMONDZ-QHCPKHFHSA-N

Description

Description générale

Building block for introduction of aspartic acid bearing TFA-labile benzyl ester protection. Benzyl group is removed by hydrogenation over Pd/C or with strong acids such as TFMSA.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Liaison

Replaces: 04-12-1272

Remarque sur l'analyse

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.0 % (a/a)
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 90.0 %
Water (K. F.): ≤ 1.0 %

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Informations légales

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable