481975

(--)-Nicotine, Ditartrate

Potent agonist of the nicotinic acetylcholine receptor.

• Synonyme(s) : (--)-Nicotine, Ditartrate, (S)-3-(1-Methyl-2-pyrrolindinyl)pyridine, Di- d-tartrate, (S)-3-(1-Methyl-2-pyrrolindinyl)pyridine, Di-d-tartrate
• Formule empirique (notation de Hill): C₁₀H₁₄N₂ · 2C₄H₆O₆
• Numéro CAS: 65-31-6
• Poids moléculaire : 462.41
• Code UNSPSC : 12352210
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Pureté: ≥98% (HPLC)
• Forme: solid
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze
• Couleur: white to off-white
• Solubilité: ethanol: 10 mg/mL; water: 10 mg/mL
• Conditions d'expédition: ambient
• Température de stockage: 10-30°C
• InChI: 1S/C10H14N2.2C4H6O6/c1-12-7-3-5-10(12)9-4-2-6-11-8-9;2*5-1(3(7)8)2(6)4(9)10/h2,4,6,8,10H,3,5,7H2,1H3;2*1-2,5-6H,(H,7,8)(H,9,10)/t;2*1-,2-/m.11/s1
• Clé InChI: RFEJUZJILGIRHQ-WBPXWQEISA-N

Description

Description générale

Potent agonist of the nicotinic acetylcholine receptor. Stimulates autonomic ganglia and skeletal muscle neuromuscular junctions.

Actions biochimiques/physiologiques

Cell permeable: no

Primary Target
Nicotinic acetylcholine receptor

Product does not compete with ATP.

Reversible: no

Avertissement

Toxicity: Highly Toxic (H)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for up to 2 weeks at 4°C or for up to 6 months at -20°C.

Autres remarques

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Rand, M.J. 1989. Prog. Brain Res. 79, 3.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS06,GHS08,GHS09
• Mention d'avertissement: Danger
• Mentions de danger: H301,H319,H330,H361d,H411
• Conseils de prudence: P202 - P260 - P264 - P273 - P304 + P340 + P310 - P305 + P351 + P338
• Classification des risques: Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Repr. 2
• Code de la classe de stockage: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): 289.8 °F
• Point d'éclair (°C): 143.2 °C