09-230

Anti-phospho-Raptor (Thr706) Antibody

from rabbit, purified by affinity chromatography

• Synonyme(s) : P150 target of rapamycin (TOR)-scaffold protein, p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats, regulatory associated protein of mTOR
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Produit purifié par: affinity chromatography
• Espèces réactives: canine, human
• Réactivité de l'espèce (prédite par homologie): horse (based on 100% sequence homology), mouse (based on 100% sequence homology), bovine (based on 100% sequence homology), dog (based on 100% sequence homology), rat (based on 100% sequence homology)
• Technique(s): dot blot: suitable; western blot: suitable
• Numéro d'accès NCBI: NP_065812
• Numéro d'accès UniProt: Q8N122
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: phosphorylation (pThr706)
• Informations sur le gène: bovine ... Rptor(507056) ; human ... RPTOR(57521)

Description

Description générale

Raptor is a subunit of mTORC1 which regulates cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino-acids. Within mTORC1, Raptor positively regulates mTORC1 activity and functions as a scaffold for recruiting mTORC1 substrates.

Spécificité

This antibody recognizes Raptor phosphorylated at Thr706.

Immunogène

Epitope: Ser706

KLH-conjugated linear peptide corresponding to human Raptor phosphorylated at and around Thr706.

Application

Detect phospho-Raptor (Thr706) using this Anti-phospho-Raptor (Thr706) Antibody validated for use in WB, DB.

Qualité

Evaluated by Dot Blot in modified and non modified peptides of phosphorylated and non-phosphorlyated Raptor protein.

Dot Blot Analysis: 1 µg/mL of this antibody detected Raptor in modified and non-modified peptides of phosphorylated and non-phosphorlyated Raptor protein.

Description de la cible

~ 150 kDa

Forme physique

Purified rabbit serum in PBS with 0.05% sodium azide.

Remarque sur l'analyse

Control
Modified and non modified peptides of phosphorylated and non-phosphorlyated Raptor protein

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable