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Key Documents

07-1407

Sigma-Aldrich

Anti-GLUT-8 Antibody, CT

from rabbit

Synonyme(s) :

Glucose transporter type 8, Glucose transporter type X1, glucose transporter X1, solute carrier family 2 (facilitated glucose transporter)

member 8, solute carrier family 2 (facilitated glucose transporter),

member 8

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Espèces réactives

human

Réactivité de l'espèce (prédite par homologie)

mouse

Technique(s)

immunohistochemistry: suitable (paraffin)

Numéro d'accès UniProt

Conditions d'expédition

wet ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... SLC2A8(29988)
mouse ... Slc2A8(56017)

Description générale

GLUT-8 is a glucose transporter facilitated by the regulation of insulin, binding cytochalasin B such that the orientation is glucose-inhibitive. In appearance, the transporter seems to be a dual-specific sugar transporter since fructose can also be inhibitive. GLUT-8 is expressed largely in the testis, where down-regulation is facilitated by estrogen. However, GLUT-8 is not highly expressed in testicular carcinoma. Lower levels of GLUT-8 are present in most other tissues.

Spécificité

Recognizes GLUT-8.

Immunogène

An 11 amino acid sequence near the C-terminus of mouse Glut-8 (Doege et al. 2000; Carayannopoulos et al. 2000)
Epitope: C-terminus

Application

Anti-GLUT-8 Antibody, C-terminus detects level of GLUT-8 & has been published & validated for use in IH(P).
Research Category
Signaling
Research Sub Category
Insulin/Energy Signaling

Qualité

Evaluated by Immunohistochemistry in human kidney tissue
Immunohistochemistry Analysis: 1:100 dilution of this lot detected GLUT-8 in human kidney tissue.

Description de la cible

Approx. 50 kDa

Liaison

Replaces: AB3140

Forme physique

Format: Purified
ImmunoAffinity Purified
Liquid in PBS with 0.1% BSA.

Stockage et stabilité

Maintain at -20°C in undiluted aliquots for up to 1 year from date of receipt. Avoid repeated freeze/thaw cycles.

Remarque sur l'analyse

Control
Human kidney tissue.

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Jimena Laporta et al.
PloS one, 8(2), e57847-e57847 (2013-03-08)
The aim of this experiment was to demonstrate the ability of feeding serotonin (5-HT; 5-hydroxytryptamine) precursors to increase 5-HT production during the transition from pregnancy to lactation and the effects this has on maternal energy metabolism in the liver and
Rachel E Bennett et al.
Acta neuropathologica communications, 8(1), 137-137 (2020-08-20)
Microangiopathy, including proliferation of small diameter capillaries, increasing vessel tortuosity, and increased capillary blockage by leukocytes, was previously observed in the aged rTg4510 mouse model. Similar gene expression changes related to angiogenesis were observed in both rTg4510 and Alzheimer's disease

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