specific only for avian Src; this antibody is excellent for distinguishing pp60src in cells transfected with v-src or c-src expression vectors.
Immunogène
Recombinant chicken pp60src
Application
Anti-avian Src Antibody, clone EC10 detects level of avian Src & has been published & validated for use in IP, WB & IC.
Qualité
routinely evaluated in (60kDa) on a RIPA lysate of chicken embryo fibroblasts (CEF)
Description de la cible
60 kDa
Forme physique
0.1M Tris-glycine, pH 7.4, 0.15M NaCl, with 0.05% sodium azide
Format: Purified
Informations légales
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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Code de la classe de stockage
12 - Non Combustible Liquids
Classe de danger pour l'eau (WGK)
WGK 1
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
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Normal cells control the growth of neighboring transformed cells independent of gap junctional communication and SRC activity.
David B Alexander, Hitoshi Ichikawa, John F Bechberger, Virginijus Valiunas, Misao Ohki et al.
Cancer Research null
Transformation-specific tyrosine phosphorylation of a novel cellular protein in chicken cells expressing oncogenic variants of the avian cellular src gene.
Proceedings of the National Academy of Sciences of the United States of America, 103(8), 2695-2700 (2006-02-16)
The transcription factor Myc plays a central role in the control of cellular proliferation. Myc expression is induced by growth factors in a pathway mediated by cellular Src (c-Src), but it is not clear whether Myc induction or activity is
Different responses in transformation of MDCK cells in 2D and 3D culture by v-Src as revealed by microarray techniques, RT-PCR and functional assays.
Toyli, M; Rosberg-Kulha, L; Capra, J; Vuoristo, J; Eskelinen, S
Laboratory Investigation; a Journal of Technical Methods and Pathology null
Many critical protein kinases rely on the Hsp90 chaperone machinery for stability and function. After initially forming a ternary complex with kinase client and the cochaperone p50(Cdc37), Hsp90 proceeds through a cycle of conformational changes facilitated by ATP binding and
Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..