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Principaux documents

LGFR100

Sigma-Aldrich

Red Fluorescent PLGA nanoparticles

100 nm average diameter

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About This Item

Code UNSPSC :
12162002
Nomenclature NACRES :
NA.23

Description

Excitation/Emission: 644/665 nm

Forme

pellets

Diamètre moyen

100 nm

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Catégories apparentées

Description générale

Particles made of poly(D,L-lactide-co-glycolide) L/G ratio of 50/50, inherent viscosity of ~0.45 dL/g.To re-constitute:
  • Warm to ambient temperature
  • Add DI water or buffer to achieve desired concentration
  • Vortex and sonicate for 5 minutes to ensure particles are well suspended

Application

Fluorescent PLGA particles for imaging and cell tracking in drug discovery. Particles can be used for fluorscent assays and drug delivery.

Informations légales

Product of Phosphorex, Inc.Degradex(RM) is a product of Phosphorex, Inc.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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Articles

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Questions

1–3 of 3 Questions  

  1. is the cy5 conjugated plga?? or cy5 encapsulated plga??

    1 answer

    1. The dye is loaded inside the nanoparticles and is not covalently attached to the surface. The type of red fluorescent dye used in the manufacture of this product is not disclosed. The excitation wavelength of the dye is approximately 644 nm with an associated emission of approximately 665 nm.

      Helpful?

  2. Hello, are these nanoparticles fucnctionalized with carboxylic acids groups on the surface?

    1 answer

    1. These nanoparticles have not been functionalized beyond a red fluorescent dye.

      Helpful?

  3. Can this product be resuspended in water? What is its stability lifetime ?

    1 answer

    1. Product LGFR100 is supplied as lyophilized powder and should be stored at -20°C in a dry environment protected from light. Product LGFR100 can be resuspended in water.

      To re-constitute:

      remove the product from freezer
      wait until temperature rises to ambient
      add DI water or buffer to the container
      vortex and sonicate for 5 minutes to ensure the microspheres are well suspended

      It is strongly recommended to use the product immediately upon resuspension because the particles begin to degrade as soon as they are introduced into an aqueous solution. If storage of particles in suspension is required, it is recommended to store at 2-8 °C to slow the degradation.

      Helpful?

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