675075

8-Mercaptooctanoic acid

95%

• Synonyme(s) : 8-Thiooctanoic acid, MOA
• Formule empirique (notation de Hill) : C₈H₁₆O₂S
• Numéro CAS: 74328-61-3
• Poids moléculaire : 176.28
• Numéro MDL: MFCD08705279
• Code UNSPSC : 12352103
• ID de substance PubChem : 24885256
• Nomenclature NACRES : NA.23

Propriétés

• Niveau de qualité: 100
• Essai: 95%
• Indice de réfraction: n20/D 1.4808
• Densité: 1.0326 g/mL at 25 °C
• Température de stockage: −20°C
• Chaîne SMILES: OC(=O)CCCCCCCS
• InChI: 1S/C8H16O2S/c9-8(10)6-4-2-1-3-5-7-11/h11H,1-7H2,(H,9,10)
• Clé InChI: FYEMIKRWWMYBFG-UHFFFAOYSA-N

Description

Description générale

8-Mercaptooctanoic acid (MOA) is an carboxylic acid terminated alkanethiol that forms self-assembled monolayers (SAMs) that facilitate subsequent surface immobilization of other molecular species.[1]

8-mercaptooctanoic acid (MOA) forms a self-assembled monolayer (SAM) on the surface of nanoparticles. MOA consists of thiol and carboxylic groups which helps in the surface treatment of different nanoparticles.[2][3]

Application

MOA is a used as a SAM for surface modification of gold electrodes for quartz crystal microbalance (QCMB) measurement.[2] It may be used as a monolayer that facilitates ferritin absorption on gold electrodes for uptake of excess iron in the cell.[3] It may also be used for preparation of nitric oxide based gold nanoparticles (NO-AuNPs) for macrophage photo-thermal therapy under NIR irradiation.[4]

MOA may form SAM that can be used in the surface modification of gold electrodes which are useful for the study of surface characteristics of ferritin.[3] It may also be used to form SAM with hydrophilic end groups to be used as a protective coating on the electrodes for efficient electron transport in semiconductor devices.[5]

This compound is used to produce hydrophilic SAMs. The resulting monolayers which are terminated with carboxylic acids can be further functionalized[6] to introduce more complex end groups. Can also be used to form a protective barrier monolayer to allow deposition of a passivating oxide layer.[7]

Autres remarques

This product should be stored in the freezer, 0 to -20 °C

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H319,H335
• Conseils de prudence: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type ABEK (EN14387) respirator filter