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452483

Sigma-Aldrich

1-Methyl-D-tryptophan

95%, for peptide synthesis

Synonyme(s) :

(2R)-2-Amino-3-(1-methyl-1H-indol-3-yl)propanoic acid, D-(+)-1-Methyltryptophan

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250 MG
44,40 €
1 G
130,00 €
10 G
905,00 €

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Changer de vue
250 MG
44,40 €
1 G
130,00 €
10 G
905,00 €

About This Item

Formule empirique (notation de Hill) :
C12H14N2O2
Numéro CAS:
Poids moléculaire :
218.25
Numéro MDL:
Code UNSPSC :
12352209
ID de substance PubChem :
Nomenclature NACRES :
NA.22

44,40 €


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Devis pour commande en gros

Nom du produit

1-Methyl-D-tryptophan, 95%

Niveau de qualité

Essai

95%

Forme

lumps and powder

Activité optique

[α]22/D +12.4°, c = 2 in acetic acid

Capacité de réaction

reaction type: solution phase peptide synthesis

Pf

242-245 °C (lit.)

Application(s)

peptide synthesis

Chaîne SMILES 

Cn1cc(C[C@@H](N)C(O)=O)c2ccccc12

InChI

1S/C12H14N2O2/c1-14-7-8(6-10(13)12(15)16)9-4-2-3-5-11(9)14/h2-5,7,10H,6,13H2,1H3,(H,15,16)/t10-/m1/s1

Clé InChI

ZADWXFSZEAPBJS-SNVBAGLBSA-N

Application

Used to prepare a number of natural products including macroline alkaloids using the Pictet-Spengler reaction of tryptophan esters with aldehydes[1] also used in the synthesis of 1-substituted indolactam precursors.[2]

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Certificats d'analyse (COA)

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Questions

1–5 of 5 Questions  
  1. I have a question regarding 1-methyl-D-tryptophan (452483). Is this suitable for cell culture study purpose? Thank you.

    1 answer
    1. This product is listed as suitable for peptide synthesis. It may be okay for cell culture, but it is not tested with that application in mind, so the suitability would need to be determined by the end user. What is tested can be found on the product COA, an example of which can be found in the 'Documentation' section of the product page.

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  2. What is Product 452483, 1-Methyl-D-tryptophan, soluble in?

    1 answer
    1. While we don't test the solubility of this product directly, we do have to dissolve it in acetic acid in order to test the optical rotation. We would also expect this to be soluble in a dilute hydrochloric acid solution (50mg/mL in 5N HCl). Both heat and sonication may be required in order to prepare a homogenous solution. Also, based on our experience with the DL (Product No. 860646) and L (Product No. 447439) forms, we would expect that dilute sodium hydroxide would also be a potential solvent (1g/100mL of 1M NaOH).

      Helpful?

  3. What is the solution stability of Product 452483, 1-Methyl-D-tryptophan?

    1 answer
    1. Unfortunately, we do not perform solution stability testing on this item or have experience with storing tryptophan solutions, so we would recommend making a fresh batch with each use.

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  4. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

  5. How should Product 452483, 1-Methyl-D-tryptophan, be stored?

    1 answer
    1. This material is stable at room temperature without any special handling precautions.

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