381551

7-Isopropoxy-3-phenyl-4H-1-benzopyran-4-one

97%

• Synonyme(s) : Ipriflavone
• Formule empirique (notation de Hill): C₁₈H₁₆O₃
• Numéro CAS: 35212-22-7
• Poids moléculaire : 280.32
• Numéro MDL: MFCD00221719
• Code UNSPSC : 12352100
• ID de substance PubChem : 24863826
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 100
• Pureté: 97%
• Pf: 116-120 °C (lit.)
• Chaîne SMILES: CC(C)Oc1ccc2c(OC=C(C2=O)c3ccccc3)c1
• InChI: 1S/C18H16O3/c1-12(2)21-14-8-9-15-17(10-14)20-11-16(18(15)19)13-6-4-3-5-7-13/h3-12H,1-2H3
• Clé InChI: SFBODOKJTYAUCM-UHFFFAOYSA-N
• Informations sur le gène: rat ... Alpl(25586)

Description

Description générale

7-Isopropoxy-3-phenyl-4H-1-benzopyran-4-one (Ipriflavone), a synthetic flavonoid, is reported to stimulate the activity of osteoblasts. It is reported to promote the deposition of calcium and the formation of mineralized nodules by newborn rat calvarial osteoblast-like (ROB) cells as well as the activity of alkaline phosphatase. Ipriflavone, an isoflavone derivative, is a new drug used to decrease bone loss in osteoporosis.

Application

7-Isopropoxy-3-phenyl-4H-1-benzopyran-4-one (Ipriflavone) has been used as a model drug in a study to functionalize the mesoporous bioactive glasses (MBG). Study suggested that since ipriflavone is a hydrophobic anti-osteoporotic drug, it easily attaches to the surface of MBG and results in long-term drug delivery.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)