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238813

Sigma-Aldrich

Acide (±)-6-hydroxy-2,5,7,8-tétraméthylchromane-2-carboxylique

97%

Synonyme(s) :

Trolox

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1 G
59,70 €
5 G
185,00 €
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599,00 €

59,70 €


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1 G
59,70 €
5 G
185,00 €
25 G
599,00 €

About This Item

Formule empirique (notation de Hill):
C14H18O4
Numéro CAS:
Poids moléculaire :
250.29
Beilstein:
1384051
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352100
ID de substance PubChem :
Nomenclature NACRES :
NA.22
Essai:
97%

59,70 €


Veuillez contacter notre Service Clients pour connaître la disponibilité de ce produit.

Devis pour commande en gros

Niveau de qualité

Essai

97%

Conditions de stockage

under inert gas

Pf

187-189 °C (lit.)

Groupe fonctionnel

carboxylic acid

Température de stockage

2-8°C

Chaîne SMILES 

Cc1c(C)c2OC(C)(CCc2c(C)c1O)C(O)=O

InChI

1S/C14H18O4/c1-7-8(2)12-10(9(3)11(7)15)5-6-14(4,18-12)13(16)17/h15H,5-6H2,1-4H3,(H,16,17)

Clé InChI

GLEVLJDDWXEYCO-UHFFFAOYSA-N

Informations sur le gène

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Description générale

L'acide (±)-6-hydroxy-2,5,7,8-tétraméthylchromane-2-carboxylique (Trolox) présente une activité de piégeage de radicaux libres et une activité antioxydante.[1][2][3][4]

Application

L'acide (±)-6-hydroxy-2,5,7,8-tétraméthylchromane-2-carboxylique (Trolox) a été utilisé dans l'évaluation de la capacité oxydante en équivalent acide 6-hydroxy-2,5,7,8-tétraméthylchromane-2-carboxylique (méthode TEAC) pour déterminer la capacité antioxydante totale de différentes espèces de fruits[5].

Conditionnement

Flacon en verre à fond plat. Le produit se trouve dans un micro-insert conique à l'intérieur du flacon.

Informations légales

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Pictogrammes

Exclamation mark

Mention d'avertissement

Warning

Mentions de danger

Classification des risques

Eye Irrit. 2 - Skin Irrit. 2

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves


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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

Dalia Mazor et al.
Biochemical and biophysical research communications, 349(3), 1171-1175 (2006-09-15)
The antioxidant properties of Bucillamine (BUC), a di-thiol compound used for treatment of rheumatoid arthritis (RA) and its possible mode of action, were investigated. BUC exhibits potent antioxidant activity similar to those of trolox and ascorbic acid. It reduces the
Functional Analogues of the Dioxygen Reduction Site in Cytochrome Oxidase:? Mechanistic Aspects and Possible Effects of CuB
Boulatov R, et al.
Journal of the American Chemical Society, 124(40), 11923-11923 (2002)
Jessica Scalzo et al.
Nutrition (Burbank, Los Angeles County, Calif.), 21(2), 207-213 (2005-02-23)
We wanted to determine the total antioxidant capacity (6-hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid equivalent antioxidant assay; TEAC) of different species and cultivars (strawberry and apple) and to characterize the TEAC among fruits of the same varieties (peach and apricot) but grafted on different
Flavonoids as antioxidants
Jovanovic S, et al.
Journal of the American Chemical Society, 116, 4846-4846 (1994)
C Giulivi et al.
Archives of biochemistry and biophysics, 303(1), 152-158 (1993-05-15)
The reactivity of Trolox C, a water-soluble analog of vitamin E, toward protein radicals formed during the oxidation of metmyoglobin and the therefrom derived molecular products was examined in terms of the ability of the phenolic antioxidant to prevent specific

Questions

1–8 of 8 Questions  
  1. Bonjour, est-ce que le trolox est soluble dans l'eau svp?

    1 answer
    1. This product has not been tested for solubility in water. Various sources suggest that this material is poorly soluble in water at 0.5 mg/mL. The solubility reportedly increases to 3 mg/mL in PBS at pH 7.2.

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  4. What is the stability of Trolox in solution? And at what temperature?

    1 answer
    1. Unfortunately, the solution stability is not determined for this product.

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  5. What is the molar absorption coefficient of Trolox ?

    1 answer
    1. The molar absorption coefficient is not determined for this product.

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  6. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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  7. How does the storage temperature relate to shipping conditions?

    1 answer
    1. The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment.

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  8. What is the solubility of Product 238813, (±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid?

    1 answer
    1. Product 238813, (±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid, has been reported to be soluble in DMSO, ethanol and dimethyl formamide. The solubility in these solvents is ~20mg/ml.

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