SOD2
superoxide dismutase 2, mitochondrial
- Human(6648) Summary: This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
- Mouse(20656) superoxide dismutase 2, mitochondrial
- Rat(24787) superoxide dismutase 2, mitochondrial
- domestic cat(101096985) superoxide dismutase 2, mitochondrial
- Horse(100034223) superoxide dismutase 2, mitochondrial
- dog(476258) superoxide dismutase 2, mitochondrial
- Zebrafish(335799) superoxide dismutase 2, mitochondrial
- chicken(374042) superoxide dismutase 2, mitochondrial
- fruit fly(36878) Superoxide dismutase 2 (Mn)
- domestic guinea pig(100135623) superoxide dismutase 2, mitochondrial
- naked mole-rat(101714164) superoxide dismutase 2, mitochondrial
- sheep(780457) superoxide dismutase 2, mitochondrial
- cow(281496) superoxide dismutase 2, mitochondrial
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