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Merck

PPARG

peroxisome proliferator-activated receptor gamma

Synonymes:
CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(5468) Summary: This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]
  • Mouse(19016) peroxisome proliferator activated receptor gamma
  • Rat(25664) peroxisome proliferator-activated receptor gamma
  • Zebrafish(557037) peroxisome proliferator activated receptor gamma
  • chicken(373928) peroxisome proliferator-activated receptor gamma
  • cow(281993) peroxisome proliferator-activated receptor gamma
  • naked mole-rat(101711078) peroxisome proliferator-activated receptor gamma
  • Goat(100861309) peroxisome proliferator-activated receptor gamma
  • domestic cat(100049014) peroxisome proliferator-activated receptor gamma
  • domestic cat(101095161) peroxisome proliferator-activated receptor gamma
  • domestic guinea pig(100729138) peroxisome proliferator-activated receptor gamma
  • sheep(443513) peroxisome proliferator-activated receptor gamma
  • dog(403606) peroxisome proliferator-activated receptor gamma

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Small Molecule - Activator

Référence du produit
Description
Espèce(s)
Ciglitizone, ≥98% (HPLC),
Espèce(s)
mouse, human
2-(p-Chlorophenoxy)-2-methylpropionic acid, 97%,
Espèce(s)
mouse, human
WY-14643, ,
Espèce(s)
rat, human, mouse
Bezafibrate, ≥98%, solid,
Espèce(s)
mouse, human

Small Molecule - Agonist

Référence du produit
Description
Espèce(s)
Rosiglitazone, ≥98% (HPLC),
Espèce(s)
human
Pioglitazone hydrochloride, ≥98% (HPLC),
Espèce(s)
human
Pioglitazone, ,
Espèce(s)
human
Pioglitazone hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Espèce(s)
human
Pioglitazone hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human

Small Molecule - Antagonist

Référence du produit
Description
Espèce(s)
GW9662, >98% (HPLC),
Espèce(s)
human
Troglitazone, ≥98% (HPLC),
Espèce(s)
human
Ciglitizone, ≥98% (HPLC),
Espèce(s)
mouse, human
GW0742, ≥98% (HPLC),
Espèce(s)
human
Acide cis-5,8,11,14,17-eicosapentaénoïque, ≥99%,
Espèce(s)
mouse, human, rat

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anticorps anti-PPAR-gamma, from rabbit, purified by affinity chromatography,
Espèces réactives
canine, feline, human, monkey, mouse, porcine
Application
immunocytochemistry
western blot
Anti-PPAR gamma antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot
Anti-PPAR-γ antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-phospho-PPAR-γ (pSer112) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
western blot
Anti-PPAR gamma 1 and 2 Antibody, phospho-specific (Ser112), ascites fluid, Chemicon®,
Espèces réactives
human, mouse
Application
ELISA
immunocytochemistry

western blot

Proteins

Référence du produit
Description
Espèce(s)
PPAR, γ human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
Espèce(s)
human
PPAR γ, ligand binding domain (204-477), GST tagged human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Pparg,
Espèce(s)
mouse
MISSION® esiRNA, targeting human PPARG,
Espèce(s)
human