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Merck

APOE

apolipoprotein E

Synonymes:
AD2, LDLCQ5, LPG
Espèce(s):
Human APOE (348), Mouse Apoe (11816), Rat Apoe (25728), naked mole-rat Apoe (101717206), domestic guinea pig Apoe (100731633), cow APOE (281004), Domestic Rabbit APOE (100009337), dog APOE (476438), domestic cat APOE (101086769)
ID UniProtKB:
P02649, B2RC15, C0JYY5, Q9P2S4
ID du gène:
  • Human(348) Summary: Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jul 2008]
  • Mouse(11816) apolipoprotein E
  • Rat(25728) apolipoprotein E
  • naked mole-rat(101717206) apolipoprotein E
  • domestic guinea pig(100731633) apolipoprotein E
  • cow(281004) apolipoprotein E
  • Domestic Rabbit(100009337) apolipoprotein E
  • dog(476438) apolipoprotein E
  • domestic cat(101086769) apolipoprotein E

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ELISA

Référence du produit
Description
Espèce(s)
RAB0613
Human APOE / Apolipoprotein E ELISA Kit, ,
Espèce(s)
human
RAB0616
Human APOE / Apolipoprotein E 4 ELISA Kit, ,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
HPA065539
Anti-APOE antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
western blot
SAB2109081
Anti-APOE (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat, zebrafish
Application
immunohistochemistry
western blot
HPA068768
Anti-APOE antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
western blot
MABN43
Anti-Apolipoprotein E4 (ApoE4) Antibody, clone 4E4, clone 4E4, from mouse,
Espèces réactives
human
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
SAB5300354
Monoclonal Anti-APOE antibody produced in mouse, clone 1H4, ascites fluid,
Espèces réactives
human
Application
ELISA
flow cytometry
immunohistochemistry
western blot

Proteins

Référence du produit
Description
Espèce(s)
SRP6303
Apolipoprotein E from human plasma, ≥95% (SDS-PAGE),
Espèce(s)
human
SRP4760
ApoE2 human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE), ≥90% (HPLC),
Espèce(s)
human
A3234
Apolipoprotein E4 human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE and HPLC), lyophilized powder,
Espèce(s)
human
L8039
Lipoprotein, high density from human plasma, ≥95% (SDS-PAGE), solution,
Espèce(s)
human
L7914
Lipoprotein, low density from human plasma, ≥95% (SDS-PAGE), solution,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
EMU031371
MISSION® esiRNA, targeting mouse Apoe,
Espèce(s)
mouse