SML0125

CPA 1 hydrate

≥98% (HPLC)

• Synonym(s): NSC 623721 hydrate, Naphtho[2,1-b:7,6-b′]difuran-2,8-dicarboxylic acid hydrate
• Empirical Formula (Hill Notation): C₁₆H₈O₆ · xH₂O
• CAS Number: 111258-00-5
• Molecular Weight: 296.23 (anhydrous basis)
• MDL number: MFCD20488061
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825175
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• color: gray-brown
• solubility: DMSO: ≥15 mg/mL
• storage temp.: 2-8°C
• SMILES string: O.OC(=O)c1cc2cc3ccc4oc(cc4c3cc2o1)C(O)=O
• InChI: 1S/C16H8O6.H2O/c17-15(18)13-4-8-3-7-1-2-11-10(6-14(21-11)16(19)20)9(7)5-12(8)22-13;/h1-6H,(H,17,18)(H,19,20);1H2
• InChI key: HKVITMNNEVXIGB-UHFFFAOYSA-N

Description

Biochem/physiol Actions

CPA 1 is a potent, selective, ATP-competitive dual inhibitor of protein kinase casein kinase 2 (CK2) and proviral insertion Moloney virus kinases (Pim kinases). CPA 1 is selective for CK2 and Pim kinases (Pim-1, Pim-2, and Pim-3) when evaluated against a panel of 112 protein kinases.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable