M8877
α-Methyl-DL-m-tyrosine
Synonym(s):
α-MMT, DL-2-Methyl-3-(3-hydroxyphenyl)alanine, AMMT
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About This Item
Empirical Formula (Hill Notation):
C10H13NO3
CAS Number:
Molecular Weight:
195.22
MDL number:
UNSPSC Code:
12352200
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storage temp.
−20°C
SMILES string
CC(N)(Cc1cccc(O)c1)C(O)=O
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S M Plosker et al.
The Journal of clinical endocrinology and metabolism, 73(3), 549-554 (1991-09-01)
The physiological role of catecholamines, particularly dopamine and norepinephrine, in the regulation of gonadotropin secretion in humans is unclear. We administered the tyrosine hydroxylase inhibitor alpha-methyl-p-tyrosine (AMPT, 500 mg at 800 and 1000 h) to five women in the early
J Bernabe et al.
Cellular and molecular neurobiology, 16(6), 617-624 (1996-12-01)
1. The present study aimed to develop a pharmacological model of catecholamine (CA) depletion in the hypothalamus during the period of its morphofunctional development, i.e. in fetal and neonatal rats of both sexes. 2. In the first series of experiments
R Boldry et al.
Pharmacology, biochemistry, and behavior, 24(2), 223-228 (1986-02-01)
We have previously synthesized a chemical analog of dopamine (DA) in which the amine group has been replaced by a permanently charged dimethylsulfonium group. In the present study, we have determined whether this compound can exert DA agonist activity in
Amfonelic acid antagonism of dopamine and norepinephrine depletion by alpha-methyl-m-tyrosine in rat brain.
R W Fuller et al.
Biochemical pharmacology, 30(14), 2025-2026 (1981-07-15)
L N Maslova et al.
Ontogenez, 15(3), 327-331 (1984-05-01)
The effects of daily intraperitoneal (150 mg/kg of body weight) injections of alpha-methyl-dl-tyrosine (MT), an inhibitor of tyrosine hydroxylase, on the 2nd to 4th, 5th to 7th or 10th to 12th days of life on the pituitary-adrenal function and brain
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