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A0650000

Amobarbital

European Pharmacopoeia (EP) Reference Standard

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About This Item

Empirical Formula (Hill Notation):
C11H18N2O3
CAS Number:
57-43-2
Molecular Weight:
226.27
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

amobarbital

manufacturer/tradename

EDQM

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IIC (Portugal)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C11H18N2O3/c1-4-11(6-5-7(2)3)8(14)12-10(16)13-9(11)15/h7H,4-6H2,1-3H3,(H2,12,13,14,15,16)

InChI key

VIROVYVQCGLCII-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Amobarbital EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Statements

H301,H336,H361d,H412

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Chronic 3 - Repr. 2 - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Lot/Batch Number

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J Simkins-Bullock
Neuropsychology review, 10(1), 41-74 (2000-06-06)
While the intracarotid amobarbital procedure (IAP) was originally utilized to lateralize speech functions as an aid in the surgical treatment of epilepsy, additional uses for the IAP have emerged including: (1) the use of the IAP to predict post-surgical memory
H Kavirajan
Harvard review of psychiatry, 7(3), 153-165 (1999-09-14)
The amobarbital interview has been a diagnostic and therapeutic tool for almost 70 years. Because safer alternatives, namely benzodiazepines, have become available over the past 30 years, its clinical use merits reexamination. Toward this end, the psychiatric literature on the
Clinical and research contributions of the intracarotid amobarbital procedure to neuropsychology.
M Jones-Gotman et al.
Brain and cognition, 33(1), 1-6 (1997-02-01)
Role of the neuropsychological evaluation and the intracarotid sodium amobarbital procedure in the surgical treatment for epilepsy.
R Rausch
Epilepsy research. Supplement, 5, 77-86 (1992-01-01)
Evidence-based practice: a reevaluation of the intracarotid amobarbital procedure (Wada test).
Sallie A Baxendale et al.
Archives of neurology, 65(6), 841-845 (2008-06-11)
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