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Supelco

Azaperone

VETRANAL®, analytical standard

Synonym(s):

1-(4-Fluorophenyl)-4-(4-(2-pyridinyl)-1-piperazinyl)-1-butanone, 4′-Fluoro-4-[4-(2-pyridyl)-1-piperazinyl]butyrophenone

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About This Item

Empirical Formula (Hill Notation):
C19H22FN3O
CAS Number:
1649-18-9
Molecular Weight:
327.40
EC Number:
216-715-8
MDL number:
MFCD00866692
UNSPSC Code:
41116107
PubChem Substance ID:
329754908
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

Fc1ccc(cc1)C(=O)CCCN2CCN(CC2)c3ccccn3

InChI

1S/C19H22FN3O/c20-17-8-6-16(7-9-17)18(24)4-3-11-22-12-14-23(15-13-22)19-5-1-2-10-21-19/h1-2,5-10H,3-4,11-15H2

InChI key

XTKDAFGWCDAMPY-UHFFFAOYSA-N

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General description

Azaperone (AZN) is a butyrophenone neuroleptic drug, used as a tranquilizer in veterinary medicine.

Application

Azaperone may be used as an analytical reference standard for the determination of the analyte in animal kidneys and blood meal by various chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG2974
BCCG6128
BCBT9584
BCBT7957
SZBD338XV

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Mari L Heinonen et al.
Veterinary anaesthesia and analgesia, 36(2), 151-157 (2009-02-26)
To investigate a combination of azaperone, detomidine, butorphanol and ketamine (DBK) in pigs and to compare it with the combination of azaperone, tiletamine and zolazepam (TZ). Prospective, randomized, blinded, cross-over study. Twelve clinically healthy crossbred pigs aged about 2 months
Determination of sedatives and adrenergic blockers in blood meal using accelerated solvent extraction and Orbitrap mass spectrometry.
Choi JH, et al.
Journal of Chromatography A, 1260(1-2), 111-119 (2012)
John H Dubinion et al.
Journal of hypertension, 28(7), 1466-1470 (2010-05-06)
We examined the role of central nervous system (CNS) endogenous melanocortin 3/4 receptors (MC3/4R) activity in controlling cardiovascular and metabolic functions in Sprague Dawley rats fed a high-fat diet (n = 6) for 10 months compared with rats fed a
T Schmidt et al.
Animal : an international journal of animal bioscience, 6(12), 1998-2002 (2012-10-04)
Injection anaesthesia with a combination of ketamine and azaperone (K/A) is discussed as a painless alternative to commonly used non-anaesthetized castration. To protect anaesthetized piglets from being crushed, they have to be separated from the sow for 3 h following
Benedict Kjaergaard et al.
European journal of emergency medicine : official journal of the European Society for Emergency Medicine, 17(3), 131-135 (2009-07-31)
In accidental hypothermia, normal signs of death are unreliable. It is generally accepted that a lifeless person is beyond the limits of rescue if plasma potassium (P-potassium) is higher than10 mmol/l. However, the rate of increase in potassium or in
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