840475C

18:1 (Δ9-Cis) PG

Avanti Research^™ - A Croda Brand

• Synonym(s): 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1′racglycerol) (sodium salt); DOPG; PG(18:1(9Z)/18:1(9Z))
• Empirical Formula (Hill Notation): C₄₂H₇₈O₁₀PNa
• CAS Number: 67254-28-8
• Molecular Weight: 797.03
• MDL number: MFCD33403202
• UNSPSC Code: 51191904
• NACRES: NA.25

Properties

• description: 1,2-dioleoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt), chloroform solution
• Assay: >99% (TLC)
• form: liquid
• packaging: pkg of 1 × 2.5 mL (840475C-25mg); pkg of 2 × 4 mL (840475C-200mg); pkg of 5 × 4 mL (840475C-500mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand
• concentration: 10 mg/mL (840475C-25mg); 25 mg/mL (840475C-200mg); 25 mg/mL (840475C-500mg)
• lipid type: cardiolipins; phospholipids
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [H][C@@](COP([O-])(OCC(O)CO)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Na+]
• InChI: 1S/C42H79O10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-41(45)49-37-40(38-51-53(47,48)50-36-39(44)35-43)52-42(46)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h17-20,39-40,43-44H,3-16,21-38H2,1-2H3,(H,47,48);/q;+1/p-1/b19-17-,20-18-;/t39?,40-;/m
• InChI key: IUVFCFQZFCOKRC-IPKKNMRRSA-M

Description

General description

Phosphoglyceride (PG) are also referred as glycerophospholipid. It is an important component of membrane bilayers. It has three-carbon backbone of glycerol, two long-chain fatty acids, esterified to hydroxyl groups on carbons 1 and 2 of the glycerol and phosphoric acid esterified to the C3 hydroxyl group of glycerol.[1] It is found at high levels in the membranes of all cells and at low levels in fat stores.[2] 1,2-dioleoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (DOPG)/18:1 (Δ9-Cis) PG has two hydroxyl groups in its head group. It is an anionic lipid.[3]

Application

• Probing the extended lipid anchorage with cytochrome c and liposomes containing diacylphosphatidylglycerol lipids.: This study investigates the interactions of cytochrome c with liposomes containing diacylphosphatidylglycerol (PG) lipids, including 18:1 (Δ9-Cis) PG. The research provides insights into the lipid anchorage and membrane dynamics, which are crucial for understanding cellular processes and developing biotechnological applications involving lipid-protein interactions (Abbott et al., 2018).

Biochem/physiol Actions

Phosphoglycerides (PG)/glycerophospholipids play a key role in cell signaling systems. It also serves as an anchor for proteins in cell membranes.[2]

Packaging

5 mL Clear Glass Sealed Ampule (840475C-200mg)

5 mL Clear Glass Sealed Ampule (840475C-25mg)

5 mL Clear Glass Sealed Ampule (840475C-500mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Pictograms: GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• Precautionary Statements: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• Target Organs: Central nervous system, Liver,Kidney
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable