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P9346

Sigma-Aldrich

Phenol solution

≥89.0% (in water)

Synonym(s):

Phenol solution

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About This Item

Empirical Formula (Hill Notation):
C6H6O
CAS Number:
108-95-2
Molecular Weight:
94.11
Beilstein:
6428463
EC Number:
203-632-7
MDL number:
MFCD00002143
UNSPSC Code:
12352104
PubChem Substance ID:
24899028
NACRES:
NA.21
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Product Name

Liquified Phenol, ≥89.0%

Agency

USP/NF
USP
suitable for SM 4500 - NH3

Quality Level

200

Assay

≥89.0%

impurities

~10% (water)

density

1.07 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

storage temp.

2-8°C

SMILES string

Oc1ccccc1

InChI

1S/C6H6O/c7-6-4-2-1-3-5-6/h1-5,7H

InChI key

ISWSIDIOOBJBQZ-UHFFFAOYSA-N

Gene Information

human ... GABRA1(2554)

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General description

Liquified Phenol is a solution of phenol containing ~10% water. It is potential as a chemical peeling agent for treating stable vitiligo and alopecia areata.[1]

Application

Liquified Phenol has been used in a study to record the one-photon (linear) absorption (1PA) and two-photon absorption 2PA spectra of Disperse Red One (DR1).[2] It may be used for deproteinization of cell lysate during the preparation of total nucleic acids.[3]

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Muta. 2 - Skin Corr. 1B - STOT RE 2

Target Organs

Nervous system,Kidney,Liver,Skin

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 2

Flash Point(F)

174.2 °F - closed cup

Flash Point(C)

79 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCW4661
MKCW4664
MKCW4662
MKCW4904
MKCS9430

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Untangling the excited states of DR1 in solution: An experimental and theoretical study.
De Boni L, et al.
The Journal of Physical Chemistry A, 112(17), 3886-3890 (2008)
J T Wachsman et al.
Journal of bacteriology, 104(2), 814-818 (1970-11-01)
Parallel studies were performed with methionineless derivatives of Escherichia coli 15 T(-) and Bacillus megaterium KM: T(-). Methylated bases are present in the total cell ribonucleic acid (RNA) of B. megaterium. The level of RNA methylation in E. coli is
S S Savant et al.
Indian journal of dermatology, venereology and leprology, 65(2), 93-98 (1999-03-01)
Chemical peeling with 88% phenol was carried out on 142 sites of stable vitiligo (hairy-126, non hairy-16) and on 69 sites of alopecia areata (AA). After cleansing and defatting, phenol was applied on affected areas till a uniform frost appeared.
Thitiporn Anunthawan et al.
Biochimica et biophysica acta, 1848(6), 1352-1358 (2015-03-15)
We investigated the mechanisms of two tryptophan-rich antibacterial peptides (KT2 and RT2) obtained in a previous optimization screen for increased killing of both Gram-negative and Gram-positive bacteria pathogens. At their minimal inhibitory concentrations (MICs), these peptides completely killed cells of
Rita A Busuttil et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 20(10), 2761-2772 (2014-03-25)
Gene-expression profiling has revolutionized the way we think about cancer and confers the ability to observe the synchronous expression of thousands of genes. The use of putative genome-level expression profiles has allowed biologists to observe the complex interactions of genes
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This page is intended to make it easier to find the consumables you need based on the analytical method you’re using. Methods included on this page come from the EPA, Standard Methods and ASTM.

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This page is intended to make it easier to find the consumables you need based on the analytical method you’re using. Methods included on this page come from the EPA, Standard Methods and ASTM.

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This page is intended to make it easier to find the consumables you need based on the analytical method you’re using. Methods included on this page come from the EPA, Standard Methods and ASTM.

Questions

1–4 of 4 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. Is this 80 percent W/W

    1 answer

    1. Liquified Phenol, Product P9346 is typically about 90 percent phenol and 10 percent water with a purity specification of ≥89.0%.

      Helpful?

  4. What is the alternative of liquid phenol in edible for commercial use.

    1 answer

    1. Unfortunately, a liquid phenol product suitable for commercial use is not offered.

      Please see the link below to review a solid phenol product suitable for pharmaceutical use:
      https://www.sigmaaldrich.com/product/mm/100201

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