P2870

Pristane

synthetic, ≥98% (GC)

• Synonym(s): Norphytane, 2,6,10,14-Tetramethylpentadecane
• Linear Formula: (CH₃)₂CH(CH₂)₃CH(CH₃)(CH₂)₃CH(CH₃)(CH₂)₃CH(CH₃)₂
• CAS Number: 1921-70-6
• Molecular Weight: 268.52
• Beilstein: 1720538
• EC Number: 217-650-8
• MDL number: MFCD00008952
• UNSPSC Code: 12352001
• PubChem Substance ID: 24898367
• NACRES: NA.25

Properties

• biological source: synthetic
• Quality Level: 200
• Assay: ≥98% (GC)
• form: liquid
• mol wt: 268.5
• storage condition: (tightly closed)
• color: colorless
• refractive index: n20/D 1.438 (lit.)
• bp: 68 °C/0.001 mmHg (lit.)
• solubility: hexane: miscible 10 % (v/v)
• density: 0.783 g/mL at 20 °C (lit.)
• storage temp.: room temp
• SMILES string: CC(C)CCCC(C)CCCC(C)CCCC(C)C
• InChI: 1S/C19H40/c1-16(2)10-7-12-18(5)14-9-15-19(6)13-8-11-17(3)4/h16-19H,7-15H2,1-6H3
• InChI key: XOJVVFBFDXDTEG-UHFFFAOYSA-N

Description

General description

Pristane, also known as norphytane, is a saturated norterpenoid alkane derived from phytane. Its immunological properties are valuable for various applications, serving as an inflammation-inducing agent in tumorigenesis and autoimmune disease induction, facilitating research on conditions like rheumatoid arthritis and lupus. Pristane′s diverse applications span acting as an immunological adjuvant, inducing autoimmune diseases, facilitating monoclonal antibody production, and serving as an energy source, making it a valuable asset in biochemical research, cell culture, and molecular biology.

Application

Pristane also acts as an immunological adjuvant for generating monoclonal antibodies in mouse ascites[1] and finds use as a biological marker. Additionally, pristane can also be used as the primary carbon and energy source for the growth of a bacterial strain, coryneform soil isolate. Its distinctive ability to induce plasmacytomas is particularly valuable for studying B-cell tumors like Burkitt′s lymphoma.
It is commonly used for priming animals, leading to granulomatous inflammation and disruption of local lymphatic drainage, resulting in increased ascitic yields. It has been used to induce systemic lupus in mice[2][3]

Pristane has been used as an inflammation-inducing agent, leading to myeloma development in BALB/c strain mice.[4] It has been used as a rheumatoid arthritis-inducing agent in rats.[5]

Features and Benefits

High quality compound suitable for multiple research applications

Other Notes

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Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319
• Precautionary Statements: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): >230.0 °F - closed cup
• Flash Point(C): > 110 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves