Transfusion medicine reviews, 25(4), 344-350 (2011-06-03)
The treatment of anemia and thrombocytopenia with allogeneic cell transfusions is an effective and well-developed technology. However, leukocyte replacement transfusion has been frustrated by the physiology of the leukocytes. To achieve effective leukocyte replacement, the continuous-flow centrifugal blood cell separator
Journal of molecular and cellular cardiology, 50(5), 910-918 (2011-03-01)
Pro-arrhythmic risk strongly limits the therapeutic value of current inotropic interventions. Istaroxime (previously PST2744) is a novel inotropic agent, significantly less pro-arrhythmic than digoxin that, in addition to block Na(+)/K(+) pump, stimulates sarcoplasmic reticulum (SR) Ca(2+) ATPase (SERCA2). Here we
Journal of chemical ecology, 37(3), 260-262 (2011-03-03)
The round goby, Neogobius melanostomus, is a highly successful invasive species in the Laurentian Great Lakes. Previous behavioral studies implied that females are attracted by pheromones to the nests of reproductive males, and that males release putative steroidal pheromones--unconjugated as
Journal of cardiovascular pharmacology, 58(2), 121-125 (2011-03-10)
In the cardiac setting in pediatrics, inotropic support is often employed based on the extrapolation from adult studies, the underlying pathophysiology, pharmacodynamics of inotropes, and anecdotal experience. Large pediatric critical care studies involving inotropic support are rare. Levosimendan, a calcium-sensitizing
To analyse the urinary steroid metabolome in a boy who had true precocious puberty after a Leydig cell tumour. Case report and detailed description of clinical and metabolic findings in a 7-year-old-boy with a Leydig cell tumour. Before surgery, the
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