Journal of pharmaceutical sciences, 70(6), 618-620 (1981-06-01)
Carbamazepine and cyheptamide have certain stereochemical features in common with phenytoin; when superimposed, two bulky hydrophobic groups in each permit the approximate apposition of two electron donor atoms. The anticonvulsant activity of each compound was determined in mice using a
Antimicrobial agents and chemotherapy, 59(11), 6682-6688 (2015-08-08)
In the treatment of HIV infection, a combination of anti-HIV drugs is commonly used in highly active antiretroviral therapy (HAART). One such combination recommended for clinical therapy consists of the two HIV protease inhibitors atazanavir and ritonavir and the HIV
Journal of medicinal chemistry, 27(5), 649-654 (1984-05-01)
The molecular structures of cyheptamide and 3-hydroxy-3- phenacyloxindole were determined by X-ray diffraction methods. The amide group in both compounds exhibits delocalization of the pi-electrons over the three atoms (N, C, and O), while the bond linking the amide to
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