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Merck

SCNN1G

sodium channel, non-voltage-gated 1, gamma subunit

Synonyms:
BESC3, ENaCg, ENaCgamma, PHA1, SCNEG
Species:
Human SCNN1G (6340), Mouse Scnn1g (20278), Rat Scnn1g (24768), domestic cat SCNN1G (101100020), cow SCNN1G (617802), domestic guinea pig Scnn1g (100270806), dog SCNN1G (489973), Domestic Rabbit SCNN1G (100008850), sheep SCNN1G (100170326), chicken SCNN1G (416579)
UniProtKB ID:
P51170, P78437, Q6PCC2, Q93023, Q93024, Q93025, Q93026, Q93027
Gene ID:
  • Human(6340) Summary: Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the gamma subunit, and mutations in this gene have been associated with Liddle syndrome. [provided by RefSeq, Apr 2009]
  • Mouse(20278) sodium channel, nonvoltage-gated 1 gamma
  • Rat(24768) sodium channel, nonvoltage-gated 1, gamma
  • domestic cat(101100020) sodium channel, non-voltage-gated 1, gamma subunit
  • cow(617802) sodium channel, nonvoltage-gated 1, gamma
  • domestic guinea pig(100270806) sodium channel, nonvoltage-gated 1 gamma
  • dog(489973) sodium channel, non-voltage-gated 1, gamma subunit
  • Domestic Rabbit(100008850) sodium channel, non-voltage-gated 1, gamma subunit
  • sheep(100170326) sodium channel, non-voltage-gated 1, gamma subunit
  • chicken(416579) sodium channel, non-voltage-gated 1, gamma subunit
  • naked mole-rat(101716529) sodium channel, non-voltage-gated 1, gamma subunit

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Small Molecule - Antagonist

Product Number
Description
Species
D207756
1,3-Diphenylguanidine, 97%,
Species
rat, mouse, human
O3764
Oxcarbazepine, ≥98% (HPLC), solid,
Species
rat, human
B5435
BIA 2-093, ≥98% (HPLC), solid,
Species
rat, human
R116
Riluzole, solid,
Species
rat, human
C8981
Carbamazepine, meets USP testing specifications,
Species
rat, human

Antibodies

Product Number
Description
Species Reactivity
Application
SAB5200107
Anti-SCNN1G antibody produced in rabbit, 1 mg/mL, affinity isolated antibody,
Species Reactivity
mouse, rat
Application
immunohistochemistry
western blot
AB3534P
Anti-Epithelial Sodium Channel-γ Antibody, Chemicon®, from rabbit,
Species Reactivity
mouse, rat
Application
ELISA
western blot
HPA071194
Anti-SCNN1G antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
SAB4301798
Anti-SCNN1G, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry

Small Molecule - Blocker

Product Number
Description
Species
1680007
Triamterene, United States Pharmacopeia (USP) Reference Standard,
Species
human
T4143
Triamterene, ≥99%,
Species
human
PHR1722
Triamterene, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Y0000837
Triamterene, European Pharmacopoeia (EP) Reference Standard,
Species
human
BP340
Triamterene, British Pharmacopoeia (BP) Reference Standard,
Species
human

Small Molecule - Inhibitor

Product Number
Description
Species
D207756
1,3-Diphenylguanidine, 97%,
Species
rat, mouse, human
A5585
5-(N-Methyl-N-isobutyl)­amiloride, ≥98% (TLC), powder,
Species
mouse, rat, human
B2417
Benzamil hydrochloride hydrate, ≥98% (HPLC),
Species
mouse, rat, human
P203
Phenamil methanesulfonate salt, solid,
Species
mouse, rat, human
A9561
5-(N,N-Hexamethylene)amiloride, ,
Species
rat, human, mouse

Proteins

Product Number
Description
Species
AG340
Epithelial Sodium Channel γ, control peptide for AB3534P, ,
Species
rat

esiRNA

Product Number
Description
Species
EHU022951
MISSION® esiRNA, targeting human SCNN1G,
Species
human