CDH1
cadherin 1, type 1, E-cadherin (epithelial)
Synonyms:
Arc-1, CD324, CDHE, ECAD, LCAM, UVO
Species:
Human CDH1 (999), Mouse Cdh1 (12550), Rat Cdh1 (83502), dog CDH1 (442858), chicken CDH1 (415860), sheep CDH1 (100294601), domestic guinea pig Cdh1 (100726210), domestic cat CDH1 (101095391), sheep CDH1 (101119747), naked mole-rat Cdh1 (101719565) ...More
UniProtKB ID:
Gene ID:
- Human(999) Summary: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq, Jul 2008]
- Mouse(12550) cadherin 1
- Rat(83502) cadherin 1
- dog(442858) cadherin 1, type 1, E-cadherin (epithelial)
- chicken(415860) cadherin 1, type 1, E-cadherin (epithelial)
- sheep(100294601) cadherin 1, type 1, E-cadherin (epithelial)
- domestic guinea pig(100726210) cadherin 1, type 1, E-cadherin (epithelial)
- domestic cat(101095391) cadherin 1, type 1, E-cadherin (epithelial)
- sheep(101119747) cadherin 1, type 1, E-cadherin (epithelial)
- naked mole-rat(101719565) cadherin 1, type 1, E-cadherin (epithelial)
- Zebrafish(114424) cadherin 1, epithelial
- cow(282637) cadherin 1, type 1, E-cadherin (epithelial)
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ELISA
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-E-Cadherin Antibody, clone 67A4, clone 67A4, Chemicon®, from mouse,
Species Reactivity
human
Application
flow cytometry
western blot
western blot
Anti-Cadherin-pan antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-E-Cadherin Antibody, clone 2Q9Y7, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-E-Cadherin (CDH1) antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM244, purified immunoglobulin,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-Cdh1 Antibody, clone AR38.2, clone AR38.2, from mouse,
Species Reactivity
human, mouse
Application
western blot
Cell Lines
Product Number
Description
Species
Proteins
Product Number
Description
Species
E-Cadherin/Fc Chimera from mouse, >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Species
mouse
E-Cadherin/ECAD/Cadherin-1/CD324 Protein human, recombinant, expressed in HEK 293 cells, ≥90% (SDS-PAGE),
Species
human