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SML0983

Sigma-Aldrich

5F-203

≥98% (HPLC)

Synonym(s):

4-(5-Fluoro-2-benzothiazolyl)-2-methyl-benzenamine, 5F203, NSC-703786

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5 MG
€78.60

About This Item

Empirical Formula (Hill Notation):
C14H11FN2S
CAS Number:
Molecular Weight:
258.31
UNSPSC Code:
12352200
NACRES:
NA.77

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Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 20 mg/mL, clear

storage temp.

2-8°C

SMILES string

Fc1cc2nc([s]c2cc1)c3cc(c(cc3)N)C

InChI

1S/C14H11FN2S/c1-8-6-9(2-4-11(8)16)14-17-12-7-10(15)3-5-13(12)18-14/h2-7H,16H2,1H3

InChI key

IFWLHIIUGSEKKE-UHFFFAOYSA-N

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1 of 4

This Item
SML2242SML0660SML1368
5F-203 ≥98% (HPLC)

SML0983

5F-203

FTBMT ≥98% (HPLC)

SML2242

FTBMT

CLP257 ≥98% (HPLC)

SML1368

CLP257

form

powder

form

powder

form

powder

form

powder

Quality Level

100

Quality Level

-

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: 20 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 15 mg/mL, clear

solubility

DMSO: 20 mg/mL, clear

color

white to beige

color

white to beige

color

white to beige

color

, white to yellow to light brown

Biochem/physiol Actions

5F-203 is a cytotoxic molecule that forms DNA adducts that lead to cell death.
5F-203 is a cytotoxic molecule that forms DNA adducts that lead to cell death. 5F-203 induces aryl hydrocarbon receptor signaling, and elevates expression of CYP1A1. Treatment of cells with 5F-203 also leads to elevation of reactive oxygen species and activation of p38, JNK and ERK.

Features and Benefits

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Articles

Cell cycle phases (G1, S, G2, M) regulate cell growth, DNA replication, and division in proliferating cells.

Apoptosis regulation involves multiple pathways and molecules for cellular homeostasis.

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