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BIS-TRIS

Name: BIS-TRIS
Brand: SIGMA
Price: 86.7 EUR

BioXtra, ≥98.0% (titration)

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Synonym(s):

2,2-Bis(hydroxymethyl)-2,2′,2″-nitrilotriethanol, 2-Bis(2-hydroxyethyl)amino-2-(hydroxymethyl)-1,3-propanediol, Bis(2-hydroxyethyl)amino-tris(hydroxymethyl)methane

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Size/SKU	Availability	Price
25 g	Check Cart for Availability	€ 86,70
100 g	Check Cart for Availability	€ 236,00
500 g	Check Cart for Availability	€ 1.000,00

About This Item

Empirical Formula (Hill Notation):

C₈H₁₉NO₅

CAS Number:

6976-37-0

Molecular Weight:

209.24

UNSPSC Code:

12161700

NACRES:

NA.25

PubChem Substance ID:

24892003

EC Number:

230-237-7

Beilstein/REAXYS Number:

2205275

MDL number:

MFCD00002853

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Properties

product line

BioXtra

Quality Segment

400

assay

≥98.0% (titration)

form

powder

impurities

≤0.005% Phosphorus (P), ≤0.1% Insoluble matter

ign. residue

≤0.1%

pH

9.0-10.1 (20-25 °C, 1 M in H₂O)

useful pH range

5.8-7.2

pKa (25 °C)

6.5

solubility

H₂O: 1 M, clear, colorless

anion traces

chloride (Cl^-): ≤0.05%, sulfate (SO₄^2-): ≤0.05%

cation traces

Al: ≤0.0005%, Ca: ≤0.005%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.005%, Mg: ≤0.0005%, NH₄⁺: ≤0.05%, Na: ≤0.005%, Pb: ≤0.001%, Zn: ≤0.0005%

application(s)

diagnostic assay manufacturing

SMILES string

OCCN(CCO)C(CO)(CO)CO

InChI

1S/C8H19NO5/c10-3-1-9(2-4-11)8(5-12,6-13)7-14/h10-14H,1-7H2

InChI key

OWMVSZAMULFTJU-UHFFFAOYSA-N

Description

Application

Optimization of Exosome Isolation: Research on optimizing exosome isolation emphasized the utility of BIS-TRIS in establishing buffer systems that enhance the accuracy of exosome size and morphology analysis, critical for diagnostic applications (Ishii et al., 2023).

Other Notes

Easily compare specifications for BIS-TRIS products with the BIS-TRIS specification table.

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This Item	B4429	137260	137276
Sigma-Aldrich B7535 BIS-TRIS	Sigma-Aldrich B4429 BIS-TRIS	SAFC 137260 BIS-TRIS	SAFC 137276 BIS-TRIS
description BioXtra, ≥98.0% (titration)	description BioPerformance Certified, suitable for cell culture, suitable for insect cell culture, ≥98.0%	description EMPROVE^® EVOLVE	description EMPROVE^® EVOLVE
assay ≥98.0% (titration)	assay ≥98.0%	assay -	assay -
product line BioXtra	product line -	product line EMPROVE^® EVOLVE	product line EMPROVE^® EVOLVE
Quality Level 400	Quality Level 400	Quality Level 400	Quality Level 400
form powder	form crystalline powder	form powder	form powder
application(s) diagnostic assay manufacturing	application(s) diagnostic assay manufacturing	application(s) -	application(s) -
solubility H₂O: 1 M, clear, colorless	solubility H₂O: 500 mg/mL, clear, colorless to very faintly yellow	solubility water: 0.1 M, clear, colorless (aqueous)	solubility water: 0.1 M, clear, colorless

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Pictograms

GHS07

Signal Word

Warning

Hazard Codes

H319

Precautionary Statements

P264 - P280 - P305 + P351 + P338 - P337 + P313

Hazard Classifications

Eye Irrit. 2

Storage Class

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

dust mask type N95 (US), Eyeshields, Gloves

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