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8.52354

Sigma-Aldrich

Fmoc-N-Me-His(Trt)-OH

Novabiochem®

Synonym(s):

Fmoc-N-Me-His(Trt)-OH, N-α-Fmoc-N-α-methyl-im-trityl-L-histidine

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About This Item

Empirical Formula (Hill Notation):
C41H35N3O4
CAS Number:
Molecular Weight:
633.73
MDL number:
UNSPSC Code:
12352200

product line

Novabiochem®

Assay

≥97.0% (HPLC)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

Fmoc

shipped in

ambient

storage temp.

15-25°C

General description

Building block for introduction of N-α-methyl-histidine amino-acid residues by Fmoc SPPS. Product has poor solubility but does dissolve upon activation in NMP with HBTU/DIPEA.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Analysis Note

Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Assay (HPLC, area%): ≥ 97.0 % (a/a)

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Articles

Unnatural amino acids, the non-proteinogenic amino acids that either occur naturally or are chemically synthesized, are becoming more and more important as tools for modern drug discovery research.

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