If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf
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About This Item
Recommended Products
Quality Level
form
beads
potency
>5000 mg/kg LD50, skin (Rabbit)
surface area
700 m2/g
loss
≤2% loss on drying, 180°C
particle size
2-5 mm
pore size
2.0-2.5 nm
pH
5-8 (20 °C, 100 g/L in H2O, slurry)
bp
2230 °C
mp
>1600 °C
bulk density
750‑800 kg/m3
storage temp.
no temp limit
SMILES string
O=[Si]=O
InChI
1S/O2Si/c1-3-2
InChI key
VYPSYNLAJGMNEJ-UHFFFAOYSA-N
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Application
- Chromatographic Applications: Silica gel is widely used as a stationary phase in chromatographic techniques for separating various chemical compounds. Innovations in silica gel modification, such as pentabromobenzyl group-modified silica gel, have enhanced the separation efficiency for metabolites like nicotinamide. This application is critical for pharmaceutical analysis and metabolomics studies, providing high precision and accuracy in quantifying biologically relevant molecules (Ozaki et al., Analytical Biochemistry, 2022).
- Environmental Pollutant Detection: Silica gel is employed in creating molecularly imprinted polymers (MIPs) that selectively recognize and bind environmental pollutants. A notable application involves embedding quantum dots in molecularly imprinted silica gel to detect aminoimidazo-azaarenes (AIAs) in food samples. This method offers high selectivity and sensitivity, making it a powerful tool for food safety and environmental monitoring (Qiao et al., Current Analytical Chemistry, 2021).
- Heavy Metal Removal from Water: Silica gel doped with specific reagents is used for the adsorption and removal of heavy metals from water samples. Recent research highlights the use of sol-gel silica doped with 3-(2-naphthoyl)-1,1-dibutylselenourea for the efficient removal of Pb(II) and Zn(II) from aqueous solutions. This application is essential for environmental remediation and ensuring water safety, showcasing the versatility and effectiveness of silica gel in addressing environmental pollutants (Mehmood et al., International Journal of Environmental Analytical Chemistry, 2022).
Analysis Note
Loss on drying (180 °C): ≤ 2 %
Water absorption capacity (24 hrs.,80 % relative humidity): ≥ 27 %
Storage Class Code
13 - Non Combustible Solids
WGK
nwg
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Customers Also Viewed
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How can I determine the shelf life / expiration / retest date of this product?
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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When do I know I need to replace the silica? What color does it change to?
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This product does not have moisture indicating properties. A good alternative would be product 1019721000, which changes color from brown to yellowish upon water uptake from the atmosphere.
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what is the color of this reagent (brown, orange & blue)?
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The silica gel product does not include an indicator. The color of this product is not apart of the test specification for this product.
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Is this silica gel only recommended for dissectors under vacuum?
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This product is typically used in desiccators, with or without a vacuum. The particle size is 2 - 5 mm which may be a factor in considering this product for other conditions or applications. See the link below for the Drying Agent product brochure.
Other desiccants in other formats are listed:
https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/124/148/br3537en-ms.pdfHelpful?
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