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Cellvento^® ModiFeed Gal+ COMP

Chemically defined cell culture feed - EMPROVE^® CCM

• UNSPSC Code: 41106213

Properties

• product name: Cellvento^® ModiFeed Gal+ COMP, Chemically defined cell culture feed - EMPROVE^® CCM
• Quality Level: 500
• description: shipped with cooling packs
• product line: Cellvento^®
• form: dry powder
• technique(s): cell culture | mammalian: suitable
• storage temp.: 2-8°C

Description

General description

Cellvento^® ModiFeed Gal+ COMP is part of the ModiFeed platform for process optimization in fed-batch. It is a highly concentrated, one-part, pH neutral feed added to replenish depleted nutrients required for cellular function and to extend the production phase in fed-batch mode, while simultanously maximizing galactosylation on the protein of interest. It is recommended in combination with the production media Cellvento^® 4CHO and EX-CELL^® Advanced CHO Fed-batch medium or other production media.

Application

Glycosylation is known to have effects on the biological activity, solubility, serum half-life, and saftey of therapeutic proteins. Control of protein glycosylation processes, such as galactosylation, while maximizing productivity is key for successful mAb process development and production. Cellvento^® ModiFeed Gal+ COMP was developed to increase galactosylation while maintaining or improving titer in CHO fed-batch processes.

Features and Benefits

• Reduced complexity in fed-batch process
• Complete feed maximizing galactosylation
• Highly concentrated to reduce required feed volume
• Compacted format for conventient handling
• Higher liquid feed stability at room temperature

Quantity

Formulated to contain 159.9 grams of powder per liter of feed.

Legal Information

CELLVENTO is a registered trademark of Merck KGaA, Darmstadt, Germany

EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany