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LM1601

Avanti

17:1 Lyso PC

Avanti Research™ - A Croda Brand LM1601, methanol solution

Synonym(s):

1-(10Z-heptadecenoyl)-sn-glycero-3-phosphocholine

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About This Item

Empirical Formula (Hill Notation):
C25H50NO7P
CAS Number:
1246304-62-0
Molecular Weight:
507.64
UNSPSC Code:
12352211
NACRES:
NA.25

form

methanol solution

packaging

pkg of 1 × 1 mL (LM1601-1EA)

manufacturer/tradename

Avanti Research™ - A Croda Brand LM1601

concentration

~10 μg/mL (Refer to C of A for lot specific concentration. )

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCCC/C=C\CCCCCC)=O

General description

Lysophosphatidylcholine (LPC) is a polar lipid, localized to the cell membranes of oxidized lipoproteins.

Application

17:1 Lyso PC has been used as an LIPID MAPS internal standard for lipid extraction from serum and quantification in liquid chromatography mass-spectrometry (LC-MS) analysis.

Biochem/physiol Actions

Lysophosphatidylcholine (LPC) is a bioactive molecule involved in various biological processes such as vascular reproduction, development and myelination. It is associated to the progression of atherosclerosis, with findings of high concentration of LPC in the lesions/plaques. Higher levels of LPC are also found in oxidatively damaged low-density lipoprotein (oxLDL) indicating cardiovascular disease. LPC is known to be implicated in neuronal diseases and cancer.

Packaging

2 mL Amber Glass Sealed Ampule (LM1601-1EA)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

also commonly purchased with this product

Product No.
Description
Pricing

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Victoria Meslier et al.
Gut (2020-02-23)
This study aimed to explore the effects of an isocaloric Mediterranean diet (MD) intervention on metabolic health, gut microbiome and systemic metabolome in subjects with lifestyle risk factors for metabolic disease. Eighty-two healthy overweight and obese subjects with a habitually
Judith Simcox et al.
Cell metabolism, 26(3), 509-522 (2017-09-07)
Cold-induced thermogenesis is an energy-demanding process that protects endotherms against a reduction in ambient temperature. Using non-targeted liquid chromatography-mass spectrometry-based lipidomics, we identified elevated levels of plasma acylcarnitines in response to the cold. We found that the liver undergoes a
A comprehensive method for lipid profiling by liquid chromatography-ion cyclotron resonance mass spectrometry
Fauland A, et al.
Journal of Lipid Research, 52(12), 2314-2322 (2011)
Alexander Fauland et al.
Journal of lipid research, 52(12), 2314-2322 (2011-10-01)
This work aims to combine chromatographic retention, high mass resolution and accuracy, MS/MS spectra, and a package for automated identification and quantitation of lipid species in one platform for lipidomic analysis. The instrumental setup elaborated comprises reversed-phase HPLC coupled to

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