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860562C

Avanti

18:1-12:0 Biotin PE

Avanti Research™ - A Croda Brand 860562C

Synonym(s):

1-oleoyl-2-(12-biotinyl(aminododecanoyl))-sn-glycero-3-phosphoethanolamine

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€619.00

€619.00

Estimated to ship on14 April 2025

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1 MG
€619.00

About This Item

Empirical Formula (Hill Notation):
C45H83N4O10PS
CAS Number:
799812-67-2
Molecular Weight:
903.20
UNSPSC Code:
12352211
NACRES:
NA.25

€619.00

Estimated to ship on14 April 2025

Request a Bulk Order

form

liquid

packaging

pkg of 1 × 1 mL (860562C-1mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 860562C

concentration

1 mg/mL (860562C-1mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCCCCCCNC(CCCC[C@]1([H])SC[C@@]2([H])[C@]1([H])NC(N2)=O)=O)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O

InChI

1S/C45H83N4O10PS/c1-2-3-4-5-6-7-8-9-10-11-12-14-17-20-23-30-42(51)56-35-38(36-58-60(54,55)57-34-32-46)59-43(52)31-24-21-18-15-13-16-19-22-27-33-47-41(50)29-26-25-28-40-44-39(37-61-40)48-45(53)49-44/h9-10,38-40,44H,2-8,11-37,46H2,1H3,(H,47,50)(H,54,55)(H2,48,49,53)/b10-9-/t38-,39+,40+,44+/m1/s1

InChI key

HACDNRDNASOHSM-IBTAXAMTSA-N

Application

18:1-12:0 Biotin PE has been used:
  • as a ligand in phosphoethanolamine binding assay[1]
  • in the generation of vesicle reconstituted with syntaxin-1A and Synaptosomal nerve-associated protein 25 (SNAP-25) vesicles[2]
  • in the preparation of biotinylated liposomes[3]

Biochem/physiol Actions

1-oleoyl-2-(12-biotinyl(aminododecanoyl))-sn-glycero-3-phosphoethanolamine, biotin PE is majorly used in the generation of lipid vesicle in supported lipid bilayer.[4] It is also used in generation of phospholipid vesicle.[5]

Packaging

5 mL Clear Glass Sealed Ampule (860562C-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system, Liver,Kidney

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

EU REACH Annex XVII (Restriction List)

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Molecular mechanisms of synaptic vesicle priming by Munc13 and Munc18
Lai Y, et al.
Neuron, 95(3), 591-607 (2017)
TIRF imaging of Fc gamma receptor microclusters dynamics and signaling on macrophages during frustrated phagocytosis
Lin J, et al.
BMC Immunology, 17(1), 5-5 (2016)
Factor VIII C1 domain residues Lys 2092 and Phe 2093 contribute to membrane binding and cofactor activity
Meems H, et al.
Blood, 114(18), 3938-3946 (2009)
Nolan C Worstell et al.
PloS one, 11(4), e0153265-e0153265 (2016-04-14)
Protein-glycan recognition is often mediated by multivalent binding. These multivalent bindings can be further complicated by cooperative interactions between glycans and individual glycan binding subunits. Here we have demonstrated a nanocube-based lipid bilayer array capable of quantitatively elucidating binding dissociation
Toh B Gang et al.
The Journal of biological chemistry, 287(51), 43116-43125 (2012-11-10)
Human C-reactive protein (CRP) protects mice from lethal Streptococcus pneumoniae infection when injected into mice within the range of 6 h before to 2 h after the administration of pneumococci. Because CRP binds to phosphocholine-containing substances and subsequently activates the
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