Skip to Content
Merck
All Photos(1)

Documents

724858

Sigma-Aldrich

Poly(N-isopropylacrylamide-co-methacrylic acid)

methacrylic acid 10 mol %, Mn 60,000

Synonym(s):

Poly(NIPAM-co-MAA), Polyacrylamide, functionalized polyNIPAM, functionalized polyacrylamide, polyNIPAM

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
(C6H11NO)m (C4H6O2)n
CAS Number:
151954-97-1
UNSPSC Code:
12162002
NACRES:
NA.23

form

solid

mol wt

Mn 60,000

composition

methacrylic acid, 10 mol %

mp

>300 °C

Mw/Mn

≤2.5

InChI

1S/C6H11NO.C4H6O2/c1-4-6(8)7-5(2)3;1-3(2)4(5)6/h4-5H,1H2,2-3H3,(H,7,8);1H2,2H3,(H,5,6)

InChI key

BGJOTKHBFYMJST-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

PNIPAM-based Smart Surfaces for Cell Sheet Tissue Engineering
Intelligent Swelling/Collapsing copolymer that can be used as a temperature- and pH-sensitive materials.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Kai Zhang et al.
Biomacromolecules, 5(4), 1248-1255 (2004-07-13)
To elucidate the mechanism of stimuli-responsive permeability and to optimize the design, the nanostructure of polymeric composite membranes, developed in our laboratory, was characterized. The membranes were prepared to contain various amounts of stimuli-responsive nanoparticles of poly(N-isopropylacrylamide-co-methacrylic acid), with or
Kai Zhang et al.
The Journal of pharmacy and pharmacology, 56(5), 611-620 (2004-05-15)
A new glucose-responsive polymeric composite membrane that provided pulsatile insulin release was developed in our laboratory previously. To develop a clinically useful insulin delivery system, this study was designed to investigate factors influencing insulin stability during delivery by this membrane.
Yunlu Dai et al.
ACS nano, 6(4), 3327-3338 (2012-03-23)
In this study, we report a new controlled release system based on up-conversion luminescent microspheres of NaYF(4):Yb(3+)/Er(3+) coated with the smart hydrogel poly[(N-isopropylacrylamide)-co-(methacrylic acid)] (P(NIPAM-co-MAA)) (prepared using 5 mol % of MAA) shell. The hybrid microspheres show bright up-conversion fluorescence
J Taillefer et al.
Journal of pharmaceutical sciences, 89(1), 52-62 (2000-02-09)
pH-responsive polymeric micelles (PM) consisting of random copolymers of N-isopropylacrylamide (NIPA), methacrylic acid (MAA), and octadecyl acrylate (ODA) were prepared and characterized. The critical aggregation concentration, as determined by a fluorescence probe technique, was approximately 10 mg/L in water and
O Meyer et al.
FEBS letters, 421(1), 61-64 (1998-02-14)
Stable liposomes were rendered pH-sensitive by complexation to a polymer that undergoes marked temperature- and pH-dependent water solubility changes. The N-isopropylacrylamide-methacrylic acid copolymer was prepared with or without octadecyl acrylate. At pH below the phase transition of the polymer, egg
View All Related Papers

Articles

Designing Temperature and pH Sensitive NIPAM Based Polymers

Poly(N-isopropylacrylamide), or PNIPAM, is a stimuli-responsive polymer that responds to changes in pH and temperature and has a LCST around 32 C.

Poly(N-isopropylacrylamide)-based Smart Surfaces for Cell Sheet Tissue Engineering

Tissue engineering has become a key therapeutic tool in the treatment of damaged or diseased organs and tissues, such as blood vessels and urinary bladders.

Stimuli-Responsive Materials as Intelligent Drug Delivery Systems

By altering the physicochemical properties, smart or intelligent drug delivery systems can be designed to deliver therapeutic molecules on-demand. Learn more about the application of stimuli-responsive materials in drug delivery.

Smart Nanofiber Meshes as a Local Drug Delivery Platform

Professor Mitsuhiro Ebara provides insights on several types of smart nanofiber mesh systems that have been explored for different drug delivery purposes.

See All

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service