Experimental and therapeutic medicine, 21(1), 51-51 (2020-12-05)
Quantitative evaluation of tic disorders (TDs) is challenging as there are few objective indicators that can be used for the assessment of treatment outcomes. 18F-Fluorodeoxyglucose (FDG) is a radioactive tracer that is able to cross the blood-brain barrier and can
The Journal of toxicological sciences, 44(2), 93-105 (2019-02-07)
Maternal exposure to 3,3'-iminodipropionitrile (IDPN) affects hippocampal neurogenesis in mouse offspring, with biphasic disruption, which facilitates neurogenesis during exposure and reduces the broad range of the granule cell lineage population at the adult stage. The present study investigated the epigenetically
Nervous and vestibular toxicities of acrylonitrile and iminodipropionitrile.
Jordi Llorens et al.
Toxicological sciences : an official journal of the Society of Toxicology, 110(1), 244-245 (2009-05-01)
Loss of balance is often due to loss of vestibular hair cells. In mammals, regeneration of functional hair cells in the mature sensory epithelium is limited; therefore, loss of sensory cells can lead to debilitating balance problems. Delivery of the
Iminodipropionitrile (IDPN) was given to rats on diets with normal copper levels, 5 ppm, and to rats on diets with high copper levels, 100 ppm. The former developed neurological symptoms, namely choreoathetoid head movements, circling and retropulsion, while the latter
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