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About This Item
Linear Formula:
CH3SO2F
CAS Number:
Molecular Weight:
98.10
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
Recommended Products
Assay
98%
reaction suitability
reaction type: click chemistry
bp
123-124 °C (lit.)
density
1.427 g/mL at 25 °C (lit.)
SMILES string
CS(F)(=O)=O
InChI
1S/CH3FO2S/c1-5(2,3)4/h1H3
InChI key
KNWQLFOXPQZGPX-UHFFFAOYSA-N
General description
Methanesulfonyl fluoride is an anticholinesterase (antiChEs), used to treat Alzheimer′s disease. It is a thrombin inhibitor.
accessory
Product No.
Description
Pricing
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 2 Oral - Skin Corr. 1B
Storage Class Code
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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D H Malin et al.
Neurobiology of aging, 14(4), 393-395 (1993-07-01)
Aged (24-month-old) rats were treated chronically with methanesulfonyl fluoride (MSF), an acetylcholinesterase (AChE) inhibitor with selectivity for central nervous system AChE, or with injection vehicle alone. Twelve 0.22 mg/kg IP injections were given over 4 weeks. MSF rats showed significantly
A W Snow et al.
Chemical research in toxicology, 1(6), 379-384 (1988-11-01)
The chemical reactivity and physical properties of methanesulfonyl fluoride (MSF) were quantitatively measured for direct comparison with those of isopropyl methylphosphonofluoridate (GB, sarin) and diisopropyl phosphorofluoridate (DFP). The chemistry involved reaction rate constant measurements of MSF hydrolysis and for reactions
L A Rodriguez et al.
Pharmacology, biochemistry, and behavior, 25(6), 1217-1221 (1986-12-01)
Perioral behaviors induced by neuroleptic drugs have been interpreted as an animal model of tardive dyskinesia. However, these behaviors have also been induced or enhanced by physostigmine, a cholinesterase inhibitor. The latter result is contradictory to the clinical effect of
Nicholas P D Liau et al.
Nature communications, 9(1), 1558-1558 (2018-04-21)
The SOCS family of proteins are negative-feedback inhibitors of signalling induced by cytokines that act via the JAK/STAT pathway. SOCS proteins can act as ubiquitin ligases by recruiting Cullin5 to ubiquitinate signalling components; however, SOCS1, the most potent member of
Weixuan Chen et al.
Biotechnology letters, 36(2), 337-340 (2013-10-09)
Fibrinogen is essential in the intrinsic and extrinsic blood coagulation process. Inhibition of fibrinogen aggregation could lead to anticoagulation effects. The availability of methods for easy quantitative evaluation of the coagulation process is critical to studying coagulation and its inhibition.
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