GC Analysis of Phthalate Esters in Perfume on SLB®-5ms (20 m x 0.18 mm I.D., 0.18 μm), Fast GC Analysis
Materialien
Analytische Säule
CONDITIONS
column
SLB-5ms, 20 m x 0.18 mm I.D., 0.18 μm (28564-U)
oven
60 °C (1 min), 10 °C/min to 330 °C (10 min)
inj. temp.
250 °C
carrier gas
helium, 0.6 mL/min, constant
liner
4 mm ID focus liner with taper
sample
cologne sample spiked at 100 μg/mL with various phthalate esters
Beschreibung
Allgemeine Beschreibung
Diethyl phthalate was detected in the unspiked sample.
Hinweis zur Analyse
Phthalate esters are commonly used as plasticizers and additives for various materials. In the case of some fragrances, diethyl phthalate is used as a solvent and deluent. Rising concern with the potential health effects of exposure to phthalate esters has lead to some controversy over their use in fragrances and other personal care products. This application illustrates the use of GC-MS to analyze a cologne sample that has been spiked at 100 ug/ml with a list of phthalate esters. The unspiked sample was found to contain diethyl phthalate.
The SLB-5ms column was chosen for the analysis due to its low bleed/MS compatibility. The nonpolar character of the phase resulted in elution of the lower boiling constituents in the cologne sample prior to most of the phthalate esters. A 20 m x 0.18 mm ID x 0.18 μm column was used to reduce overall analysis time.
Rechtliche Hinweise
SLB is a registered trademark of Merck KGaA, Darmstadt, Germany