- Understanding the relationship between DNA methylation and histone lysine methylation.
Understanding the relationship between DNA methylation and histone lysine methylation.
Biochimica et biophysica acta (2014-02-25)
Nathan R Rose, Robert J Klose
PMID24560929
ZUSAMMENFASSUNG
DNA methylation acts as an epigenetic modification in vertebrate DNA. Recently it has become clear that the DNA and histone lysine methylation systems are highly interrelated and rely mechanistically on each other for normal chromatin function in vivo. Here we examine some of the functional links between these systems, with a particular focus on several recent discoveries suggesting how lysine methylation may help to target DNA methylation during development, and vice versa. In addition, the emerging role of non-methylated DNA found in CpG islands in defining histone lysine methylation profiles at gene regulatory elements will be discussed in the context of gene regulation.
MATERIALIEN
Produktnummer
Marke
Produktbeschreibung
Sigma-Aldrich
L-Lysin -monohydrochlorid, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 98.5-101.0%
Supelco
L-Lysin -monohydrochlorid, Pharmaceutical Secondary Standard; Certified Reference Material
Lysin -hydrochlorid, European Pharmacopoeia (EP) Reference Standard
Supelco
L-Lysin -monohydrochlorid, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
Lysin-acetat, European Pharmacopoeia (EP) Reference Standard