Direkt zum Inhalt
Merck
Alle Fotos(2)

Dokumente

V900421

Sigma-Aldrich

Uridin

Vetec™, reagent grade, 99%

Synonym(e):

1-β-D-Ribofuranosyluracil, Uracil-1-β-D-Ribofuranosid

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise
Alle Fotos(2)

About This Item

Empirische Formel (Hill-System):
C9H12N2O6
CAS-Nummer:
58-96-8
Molekulargewicht:
244.20
Beilstein:
754902
MDL-Nummer:
MFCD00006526
UNSPSC-Code:
12352204
PubChem Substanz-ID:
329829829

Qualität

reagent grade

Produktlinie

Vetec™

Assay

99%

Form

powder

mp (Schmelzpunkt)

163-167 °C (lit.)

SMILES String

OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=CC(=O)NC2=O

InChI

1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1

InChIKey

DRTQHJPVMGBUCF-XVFCMESISA-N

Suchen Sie nach ähnlichen Produkten? Aufrufen Leitfaden zum Produktvergleich

Allgemeine Beschreibung

Uridine is a pyrimidine nucleoside composed of uracil and ribose that is readily taken up by the brain. This compound is synthesized de novo in mammals. It is found circulating in the blood and cerebrospinal fluid.

Biochem./physiol. Wirkung

Uridine is an essential compound involved in maintaining cellular function and energy metabolism. It aids in multiple biological processes, including RNA synthesis, the synthesis of biomembranes, and glycosylation. Furthermore, uridine serves as a precursor molecule for UDP-glucose, a vital component in the synthesis and storage of glycogen in the liver. In addition, studies have shown that uridine reduces cytotoxicity and improves neurophysiological functions. It is involved in regulating various normal physiological processes in the body, including the cardio-circulatory, reproductive, peripheral and central nervous, and respiratory systems.

Rechtliche Hinweise

Vetec is a trademark of Merck KGaA, Darmstadt, Germany

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Kunden haben sich ebenfalls angesehen

Slide 1 of 5

1 of 5

Aniline Blue solution 2.5% in 2% acetic acid

Sigma-Aldrich

B8563

Aniline Blue solution

D-(+)-Glukose powder, BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture, ≥99.5%

Sigma-Aldrich

G7021

D-(+)-Glukose

D-(+)-Galactose ≥99% (HPLC), BioReagent, suitable for cell culture, suitable for insect cell culture

Sigma-Aldrich

G5388

D-(+)-Galactose

Triton™ X-100 BioXtra

Sigma-Aldrich

T9284

Triton™ X-100

Dimethylsulfoxid Hybri-Max™, sterile-filtered, BioReagent, suitable for hybridoma, ≥99.7%

Sigma-Aldrich

D2650

Dimethylsulfoxid

G P Connolly et al.
Trends in pharmacological sciences, 20(5), 218-225 (1999-06-04)
There are many disorders of pyrimidine metabolism and those that involve an alteration in uridine metabolism have neurological and systemic effects, which provide insights into the biological activity of uridine and its analogues. Studies of the metabolism and actions of
Ian E Crandall et al.
Journal of medicinal chemistry, 56(6), 2348-2358 (2013-02-16)
Resistance by Plasmodium falciparum to almost all clinically used antimalarial drugs requires the development of new classes of antimalarials. 6-Iodouridine (15), a novel and potent inhibitor of orotidine 5'-monophosphate decarboxylase (ODCase), exhibited efficacy in a mouse model infected by P.
Laure Jobert et al.
Molecular cell, 49(2), 339-345 (2012-12-19)
Single-strand-selective monofunctional uracil-DNA glycosylase 1 (SMUG1) is a base excision repair enzyme that removes uracil and oxidised pyrimidines from DNA. We show that SMUG1 interacts with the pseudouridine synthase Dyskerin (DKC1) and colocalizes with DKC1 in nucleoli and Cajal bodies.
Juma A M Ali et al.
Molecular pharmacology, 83(2), 439-453 (2012-11-29)
African trypanosomes are capable of both pyrimidine biosynthesis and salvage of preformed pyrimidines from the host. However, uptake of pyrimidines in bloodstream form trypanosomes has not been investigated, making it difficult to judge the relative importance of salvage and synthesis
Che C Colpitts et al.
Journal of virology, 87(7), 3640-3654 (2013-01-04)
Entry of enveloped viruses requires fusion of viral and cellular membranes. Fusion requires the formation of an intermediate stalk structure, in which only the outer leaflets are fused. The stalk structure, in turn, requires the lipid bilayer of the envelope
Alle zugehörigen Dokumente anzeigen

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.