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Merck

1508901

USP

Pentoxifyllin

United States Pharmacopeia (USP) Reference Standard

Synonym(e):

3,7-Dimethyl-1-(5-oxohexyl)-xanthin, Trental

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200 MG

€ 407,00

€ 407,00


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Über diesen Artikel

Empirische Formel (Hill-System):
C13H18N4O3
CAS-Nummer:
Molekulargewicht:
278.31
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:

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Unterstützung erhalten

InChI key

MQGNNJQTNFHNHK-UHFFFAOYSA-N

SMILES string

CN1C=NC2C1C(=O)N(CCCCC(C)=O)C(=O)N2C

InChI

1S/C13H20N4O3/c1-9(18)6-4-5-7-17-12(19)10-11(14-8-15(10)2)16(3)13(17)20/h8,10-11H,4-7H2,1-3H3

grade

pharmaceutical primary standard

API family

pentoxifylline

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

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Dieser Artikel
P0510000PHR3218P1784
manufacturer/tradename

USP

manufacturer/tradename

EDQM

manufacturer/tradename

-

manufacturer/tradename

-

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

grade

certified reference material, pharmaceutical secondary standard

grade

-

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical

application(s)

-

format

neat

format

neat

format

-

format

-

API family

pentoxifylline

API family

pentoxifylline

API family

pentoxifylline

API family

-

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Pentoxifylline USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Pentoxifylline Compounded Oral Suspension
  • Pentoxifylline Extended-Release Tablets

Biochem/physiol Actions

Phosphodiesterase-Inhibitor; hemmt die Synthese des Tumornekrosefaktors α (TNF-α).

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

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signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Lact.

Lagerklasse

11 - Combustible Solids


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Donghao Lu et al.
The Cochrane database of systematic reviews, 1, CD007677-CD007677 (2012-01-20)
Endometriosis is a chronic, recurring condition that occurs during the reproductive years. It is characterized by endometrial tissue developing outside the uterine cavity. This endometrial tissue development is dependent on oestrogen produced primarily by the ovaries and, therefore, traditional management
Seray Külcü Çakmak et al.
Inflammation & allergy drug targets, 11(6), 422-432 (2012-06-12)
Pentoxifylline is methylxanthine derivative which is used in microcirculatory disorders as a vasoactive drug. Novel immunomodulatory properties of pentoxifylline have been reported including the down regulation of tumour necrosis factor-α synthesis and other inflammatory cytokines. Studies have shown that pentoxifylline
H V Groesdonk et al.
Der Anaesthesist, 58(11), 1136-1143 (2009-11-06)
Initially introduced as a rheologic agent for use in intermittent claudication due to peripheral artery disease and in ischemic cerebrovascular disease, the methylxanthine derivative pentoxifylline (PTX) has been shown to possess several anti-inflammatory properties which make this drug an interesting
Kate Whitfield et al.
The Cochrane database of systematic reviews, (4)(4), CD007339-CD007339 (2009-10-13)
Alcoholic hepatitis is a life-threatening disease, with an average mortality of approximately 40%. There is no widely accepted, effective treatment for alcoholic hepatitis. Pentoxifylline is used to treat alcoholic hepatitis, but there has been no systematic review to assess its
Donghao Lv et al.
The Cochrane database of systematic reviews, (3)(3), CD007677-CD007677 (2009-07-10)
Endometriosis is a chronic, recurring condition that occurs during the reproductive years. It is characterized by endometrial tissue developing outside the uterine cavity. This endometrial tissue development is dependent on estrogen produced primarily by the ovaries and, therefore, traditional management

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