1502508

Penicillin-G-kalium

United States Pharmacopeia (USP) Reference Standard

• Synonym(e): Penicillin G Kaliumsalz, Benzylpenicillin Kaliumsalz
• Empirische Formel (Hill-System): C₁₆H₁₇KN₂O₄S
• CAS-Nummer: 113-98-4
• Molekulargewicht: 372.48
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329750683
• MDL number: MFCD00036193
• Beilstein/REAXYS Number: 3832841

Eigenschaften

• grade: pharmaceutical primary standard
• agency: USP
• API family: penicillin & derivatives
• form: powder
• manufacturer/tradename: USP
• application(s): USP Biologics; pharmaceutical (small molecule)
• format: neat
• SMILES string: [K+].[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)Cc3ccccc3)C([O-])=O
• InChI: 1S/C16H18N2O4S.K/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);/q;+1/p-1/t11-,12+,14-;/m1./s1
• InChI key: IYNDLOXRXUOGIU-LQDWTQKMSA-M

Beschreibung

General description

Find answers to frequently asked questions on USP products in USP FAQs.

Penicillin G potassium is a natural β-lactam antibiotic that targets bacterial cell wall synthesis by inhibiting transpeptidase enzymes. It is effective against non-β-lactamase-producing Gram-positive organisms. The USP standard facilitates microbiological potency tests and purity analysis.

The USP biologics antibiotics category includes a wide range of antimicrobial agents that are essential in treating bacterial infections. These antibiotics are derived from various natural sources or synthesized to combat specific pathogens effectively. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of antibiotic therapeutics throughout their lifecycle.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

Application

Penicillin G potassium USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Penicillamine
• Penicillin G Benzathine
• Penicillin G Benzathine and Penicillin G Procaine Injectable Suspension
• Penicillin G Benzathine Injectable Suspension
• Penicillin G Potassium
• Penicillin G Potassium for Injection
• Penicillin G Potassium for Oral Solution

Biochem/physiol Actions

Wirkungsweise: Penicillin G wirkt durch Hemmung der Zellwandsynthese durch die Bindung an Penicillin bindende Proteine (PBP), um die Vernetzung der Peptidoglycan-Kette zu hemmen.

Antimikrobielles Spektrum: Diese Produkt ist wirksam gegen grampositive und gramnegative Bakterien.

Other Notes

Sales restrictions may apply.

This product is part of the USP Biologics program.

Sicherheitshinweise

• pictograms: GHS07
• signalword: Warning
• hcodes: H317
• Hazard Classifications: Skin Sens. 1
• Lagerklasse: 11 - Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• pcodes: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364