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Merck

V4015

Sigma-Aldrich

Verbascosid

≥99% (HPLC)

Synonym(e):

Acetosid, Kusaginin

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10 MG
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About This Item

Empirische Formel (Hill-System):
C29H36O15
CAS-Nummer:
Molekulargewicht:
624.59
MDL-Nummer:
UNSPSC-Code:
12352200
PubChem Substanz-ID:
NACRES:
NA.25

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Qualitätsniveau

Assay

≥99% (HPLC)

Anwendung(en)

metabolomics
vitamins, nutraceuticals, and natural products

Lagertemp.

room temp

SMILES String

C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](OCCc3ccc(O)c(O)c3)O[C@H](CO)[C@H]2OC(=O)\C=C\c4ccc(O)c(O)c4)[C@H](O)[C@H](O)[C@H]1O

InChI

1S/C29H36O15/c1-13-22(36)23(37)24(38)29(41-13)44-27-25(39)28(40-9-8-15-3-6-17(32)19(34)11-15)42-20(12-30)26(27)43-21(35)7-4-14-2-5-16(31)18(33)10-14/h2-7,10-11,13,20,22-34,36-39H,8-9,12H2,1H3/b7-4+/t13-,20+,22-,23+,24+,25+,26+,27+,28+,29-/m0/s1

InChIKey

FBSKJMQYURKNSU-ZLSOWSIRSA-N

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Allgemeine Beschreibung

Verbascoside, also known as acteoside, is a hydrophilic plant compound first isolated from mullein (Verbascum sinuatum L.).[1] The chemical structure of verbascoside comprises hydroxyphenylethyl and cinnamic acid moieties bound to a β-glucopyranose via a glycosidic bond.[1]

Anwendung

Verbascoside has been used:
  • as a reference standard for high-performance liquid chromatography (HPLC) analysis[2]
  • as a reference standard for detection of phenolic compounds in olive mill wastewater and pomace by high-performance liquid chromatography (HPLC)-diode-array detector (DAD)-qTOF system[3]
  • to test its anti-viral activity against respiratory syncytial virus (RSV) in HEP2 cells and A549 cells[4]

Biochem./physiol. Wirkung

Phenylethanoidglykosid. Antioxidans und Antiproliferativum.
Verbascoside has anti-inflammatory and photoprotective properties.[5] It has shown neuroprotective effects on PC12 neuronal cells against neurotoxicity.[6] Verbascoside is proven to be a potent inhibitor of xanthine oxidase (XOD) in in vitro studies.[7]

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Kiramage Chathuranga et al.
Viruses, 11(7) (2019-07-07)
The herbs Plantago asiatica and Clerodendrum trichotomum have been commonly used for centuries in indigenous and folk medicine in tropical and subtropical regions of the world. In this study, we show that extracts from these herbs have antiviral effects against
Guo-Qing Sheng et al.
European journal of pharmacology, 451(2), 119-124 (2002-09-17)
The neuroprotective effects of verbascoside, one of phenylpropanoid glucoside isolated from the Chinese herbal medicine Buddleja officinalis Maxim, on 1-methyl-4-phenylpyridinium ion (MPP(+)) induced apoptosis and oxidative stress in PC12 neuronal cells were investigated. Treatment of PC12 cells with MPP(+) for
Yin Wan et al.
International journal of biological macromolecules, 93(Pt A), 609-614 (2016-11-05)
In this study, we analyzed the inhibitory effect of verbascoside against xanthine oxidase (XOD) in vitro by using animal model and in vivo by direct inhibition assay. Results showed that verbascoside could reduce uric acid in rat serum and inhibit
Kalina Alipieva et al.
Biotechnology advances, 32(6), 1065-1076 (2014-07-23)
Phenylethanoid glycosides are naturally occurring water-soluble compounds with remarkable biological properties that are widely distributed in the plant kingdom. Verbascoside is a phenylethanoid glycoside that was first isolated from mullein but is also found in several other plant species. It
Angela Cardinali et al.
Journal of agricultural and food chemistry, 60(7), 1822-1829 (2012-01-25)
Olive oil processing industries generate substantial quantities of phenolic-rich byproducts, which could be valuable natural sources of antioxidants. This work is focused on the recovery and structural characterization of antioxidant compounds from olive mill wastewater (OMWW), a polluting byproduct of

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