V2390

VRT-532

≥98% (HPLC)

• Synonym(e): 4-Methyl-2-(5-phenyl-1H-pyrazol-3-yl)phenol, CFpot 532
• Empirische Formel (Hill-System): C₁₆H₁₄N₂O
• CAS-Nummer: 38214-71-0
• Molekulargewicht: 250.30
• UNSPSC Code: 12352200
• Assay: ≥98% (HPLC)
• Form: solid

Eigenschaften

• assay: ≥98% (HPLC)
• form: solid
• solubility: DMSO: >20 mg/mL
• storage temp.: −20°C
• InChI: 1S/C16H14N2O/c1-11-7-8-16(19)13(9-11)15-10-14(17-18-15)12-5-3-2-4-6-12/h2-10,19H,1H3,(H,17,18)
• InChI key: AQWKVJFRGORALM-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

VRT-532 is a mutated G551D CFTR corrector.

VRT-532 is a mutated G551D CFTR corrector. VRT-532 mediates G551D-CFTR by enhancement of ATP affinity of the mutant. VRT-532 also potentiates F508del mutated CFTR and works specifically on mutant CFTR rather than other membrane proteins.

Features and Benefits

This compound is featured on the Chloride Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• pictograms: GHS05,GHS07
• signalword: Danger
• hcodes: H302,H318
• pcodes: P280 - P301 + P312 + P330 - P305 + P351 + P338 + P310
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable