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T4924

Sigma-Aldrich

Theophylline-[8-3H]

aqueous ethanol solution (1:1)

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About This Item

Lineare Formel:
C7H8O2N4
CAS-Nummer:
134459-03-3
Molekulargewicht:
180.16
MDL-Nummer:
MFCD00190028
UNSPSC-Code:
12352200
PubChem Substanz-ID:
24900236

Form

aqueous ethanol solution (1:1)

Kennzeichnungsgrad

15-30 Ci/mmol

Versandbedingung

dry ice

Lagertemp.

−20°C

SMILES String

[H]c1nc2N(C)C(=O)N(C)C(=O)c2[nH]1

Angaben zum Gen

human ... ADORA1(134) , ADORA2A(135) , ADORA2B(136) , ADORA3(140)
mouse ... Adora2b(11541)
rat ... Adora1(29290) , Adora2a(25369) , Adora2b(29316) , Pde1b(29691) , Pde3a(50678)

Analysenzertifikate (COA)

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Laura López-Cruz et al.
Behavioural brain research, 270, 213-222 (2014-05-27)
Caffeine and theophylline are methylxanthines that are broadly consumed, sometimes at high doses, and act as minor psychostimulants. Both are nonselective adenosine antagonists for A1 and A2A receptors, which are colocalized with dopamine D1 and D2 receptors in striatal areas.
Diego Caccavo et al.
Molecular pharmaceutics, 12(2), 474-483 (2014-12-17)
In this work the behavior of hydrogel-based matrices, the most widespread systems for oral controlled release of pharmaceuticals, has been mathematically described. In addition, the calculations of the model have been validated against a rich set of experimental data obtained
Rania O Salama et al.
Drug delivery and translational research, 4(3), 256-267 (2015-03-20)
A novel approach to concurrently deliver oral and inhaled drugs as a single formulation is presented. A triple therapy containing theophylline (THEO; orally delivered) with budesonide (BUD) and terbutaline (TERB; as single and co-spray-dried inhaled powders) was prepared as an
Naoto Fujii et al.
The Journal of physiology, 593(11), 2515-2525 (2015-03-27)
In humans in vivo, the mechanisms behind ATP-mediated cutaneous vasodilatation along with whether and how ATP increases sweating remains uncertain. Recent work has implicated nitric oxide synthase (NOS), cyclooxygenase (COX) and/or adenosine in the modulation of cutaneous vasodilatation and sweat
Lauriane Goldwirt et al.
Cancer chemotherapy and pharmacology, 74(1), 185-193 (2014-05-29)
Glioblastoma (GBM), the most common primary brain tumor in adults, is usually rapidly fatal with median survival duration of only 15 months and a 3-year survival rate of <7 %. Temozolomide (TMZ) is the only anticancer drug that has improved
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