T3149

Tocinoic acid

≥97% (HPLC)

• Synonym(e): [Ile³]-Pressinoic acid
• Empirische Formel (Hill-System): C₃₀H₄₄N₈O₁₀S₂
• CAS-Nummer: 34330-23-9
• Molekulargewicht: 740.85
• MDL-Nummer: MFCD00076737
• UNSPSC-Code: 51111800
• PubChem Substanz-ID: 24900110

Eigenschaften

• Assay: ≥97% (HPLC)
• Form: powder
• Methode(n): cell culture | mammalian: suitable
• Lagertemp.: −20°C
• SMILES String: CCC(C)C1NC(=O)C(Cc2ccc(O)cc2)NC(=O)C(N)CSSCC(NC(=O)C(CC(N)=O)NC(=O)C(CCC(N)=O)NC1=O)C(O)=O
• InChI: 1S/C30H44N8O10S2/c1-3-14(2)24-29(46)34-18(8-9-22(32)40)26(43)36-20(11-23(33)41)27(44)37-21(30(47)48)13-50-49-12-17(31)25(42)35-19(28(45)38-24)10-15-4-6-16(39)7-5-15/h4-7,14,17-21,24,39H,3,8-13,31H2,1-2H3,(H2,32,40)(H2,33,41)(H,34,46)(H,35,42)(H,36,43)(H,37,44)(H,38,45)(H,47,48)
• InChIKey: ITRWUGOBSKHPTA-UHFFFAOYSA-N

Beschreibung

Amino Acid Sequence

Cys-Tyr-Ile-Gln-Asn-Cys [Disulfide bridge: 1-6]

Anwendung

Tocinoic acid is an oxytocin receptor antagonist and is used to study effects of oxytocin and 5-HT1A receptors on the prosocial effects of 3,4 methylenedioxymethamphetamine (MDMA; ecstasy). It can also be used as a test compound for studying whether the release of protein disulfide isomerase activity is stimulated by activated platelets or not.

Biochem./physiol. Wirkung

Tocinoic acid contains the ring structure of oxytocin that inhibits the release of melanocyte-stimulating hormones (MSH) the rat pituitary in vitro.

Sonstige Hinweise

N-terminal hexapeptide fragment of oxytocin.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)