SRP4248

MIP-1beta from mouse

recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)

• Synonym(e): CCL4, MIP-1- β, Macrophage inflammatory protein 1-β, Small inducible cytokine A4, T-cell activation protein 2
• MDL-Nummer: MFCD00213006
• UNSPSC-Code: 12352200
• NACRES: NA.32

Eigenschaften

• Biologische Quelle: mouse
• Rekombinant: expressed in E. coli
• Assay: ≥98% (HPLC); ≥98% (SDS-PAGE)
• Form: lyophilized
• Mol-Gew.: ~7.8 kDa
• Verpackung: pkg of 10 μg
• Verunreinigungen: endotoxin, tested
• NCBI-Hinterlegungsnummer: P14097
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Angaben zum Gen: mouse ... Ccl4(20303)

Beschreibung

Allgemeine Beschreibung

Mouse macrophage inflammatory protein-1β (MIP-1β) is a 7.8 kDa protein containing 69 amino acid residues. It plays an important role in the inflammatory response of blood monocytes and tissue macrophages.
MIP-1β is mainly generated by monocytes and lymphocytes. It is a member of CC family of chemokine intercrine cytokine. MIP-1β shares 70% similarity with MIP-1α. It is localized to a number of tissues such as smooth muscles, monocytes, neutrophils, mast cells, fibroblast B and T lymphocytes.

Biochem./physiol. Wirkung

Macrophage inflammatory protein-1 β (MIP-1β) promotes myelopoietic cellular growth and induces leukocyte chemoattraction. MIP-1β is an effective HIV infection suppressor.

Physikalische Form

Lyophilized without any additives.

Rekonstituierung

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Reconstitute in water to a concentration of 0.1-1.0 mg/mL. This solution can then be diluted into other aqueous buffers.