SML2797

UNBS5162

≥98% (HPLC)

• Synonym(e): N-[2-[2-(Dimethylamino)ethyl]-2,3-dihydro-1,3-dioxo-1H-benz[de]isoquinolin-5-yl]urea, UNBS 5162, [2-[2-(Dimethylamino)ethyl]-1,3-dioxobenzo[de]isoquinolin-5-yl]urea
• Empirische Formel (Hill-System): C₁₇H₁₈N₄O₃
• CAS-Nummer: 956590-23-1
• Molekulargewicht: 326.35
• UNSPSC Code: 12352200
• NACRES: NA.77
• MDL number: MFCD22380608
• Assay: ≥98% (HPLC)
• Form: powder
• Quality level: 100

Eigenschaften

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: −20°C
• SMILES string: [n]1([c](c2c3c([c]1=O)cccc3cc(c2)NC(=O)N)=O)CCN(C)C
• InChI: 1S/C17H18N4O3/c1-20(2)6-7-21-15(22)12-5-3-4-10-8-11(19-17(18)24)9-13(14(10)12)16(21)23/h3-5,8-9H,6-7H2,1-2H3,(H3,18,19,24)
• InChI key: WCKZRLOUKYFJDY-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

UNBS5162, an amonafide (naphthalimide) derivative, is a potent antitumor agent that inhibits tumor proliferation, progression and invasiveness. UNBS5162 is a pan-antagonist of CXCL chemokine expression. It appears that UNBS5162 inhibits melanoma progression through inhibition of the AKT/mTOR signaling pathway.

pan-antagonist of CXCL chemokine expression

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable